Dr. Lim, Carmay ’s Lab林小喬 博士 實驗室

Factors Controlling the Mechanism of NAD(+) Non-Redox Reactions.

β-Nicotinamide adenine dinucleotide (NAD(+)) is an indispensable coenzyme or substrate for enzymes involved in catalyzing redox and non-redox reactions. ADP-ribosylating enzymes catalyze cleavage of the nicotinamide-glycosyl bond of NAD(+) and addition of a nucleophilic group from their substrate proteins to