Dr. Chern, Yijuang 陳儀莊博士 HIGHLIGHT DETAIL 重要成果詳細內容

HIGHLIGHT DETAIL
重要成果詳細內容

Type VI adenylyl cyclase (AC6) regulates neurite extension by binding to Snapin and Snap25.

Mol. Cell. Biol., Oct 10, 2011

3' -5' -Cyclic adenosine monophosphate (cAMP) is an important second messenger which regulates neurite outgrowth. We demonstrate herein that type VI adenylyl cyclase (AC6), an enzyme which catalyzes cAMP synthesis, regulates neurite outgrowth by direct interaction with a binding protein (Snapin) of Snap25 at the N-terminus of AC6 (AC6-N). We first showed that AC6 expression increased during

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Cell Mol Life Sci. May 25, 2012
Type VI adenylyl cyclase (AC6) regulates neurite extension by binding to Snapin and Snap25.
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Nuclear translocation of AMPK-α1 potentiates striatal neurodegeneration in Huntington』s disease.
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Molecular & Cellular Proteomics. Jan 31, 2007
Dysregulation of C/EBPa by mutant Huntingtin causes the urea cycle deficiency in Huntington's disease.
Hum Mol Genet. Jan 09, 2007

HIGHLIGHT DETAIL重要成果詳細內容

Type VI adenylyl cyclase (AC6) regulates neurite extension by binding to Snapin and Snap25.

List of Highlights文件紀錄

HIGHLIGHT DETAIL
重要成果詳細內容

List of Highlights
文件紀錄