Dr. Huang, Yi-Shuian 黃怡萱 博士

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重要成果


  • CPEB3-downregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice
    Neuropsychopharmacology, May 03, 2021
        Susceptibility or resilience to posttraumatic stress disorder (PTSD) depends on one's ability to appropriately adjus ......
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  • CMTR1-Catalyzed 2'-O-Ribose Methylation Controls Neuronal Development by Regulating Camk2α Expression Independent of RIG-I Signaling
    Cell Reports, Oct 20, 2020
    Summary Eukaryotic mRNAs are 5′ end capped with a 7-methylguanosine, which is important for processing and translation of mRNAs. ......
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  • CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis
    Journal of Biomedical Science, Apr 15, 2020
    Background Alveologenesis is the final stage of lung development to form air-exchanging units between alveoli and blood vessels. Genetic ......
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  • CPEB2‐dependent translation of long 3′‐UTR Ucp1 mRNA promotes thermogenesis in brown adipose tissue
    EMBO J, Sep 03, 2018
    Expression of mitochondrial proton transporter uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) is essential for mammalian thermoge ......
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  • Olfactory-Experience- and Developmental-Stage-Dependent Control of CPEB4 Regulates c-Fos mRNA Translation for Granule Cell Survival
    Cell Reports, Nov 21, 2017
    Summary: Mammalian olfactory bulbs (OBs) require continuous replenishment of interneurons (mainly granule cells [GCs]) to support local cir ......
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