Dr. Huang, Yi-Shuian 黃怡萱 博士

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  • Generation and Role of Calpain-Cleaved 17-kDa Tau Fragment in Acute Ischemic Stroke
    Molecular Neurobiology, Aug 19, 2021
        Stroke is the leading cause of permanent disability and death in the world. The therapy for acute stroke is still limite ......
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  • CPEB3-downregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice
    Neuropsychopharmacology, May 03, 2021
        Susceptibility or resilience to posttraumatic stress disorder (PTSD) depends on one's ability to appropriately adjus ......
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  • CMTR1-Catalyzed 2'-O-Ribose Methylation Controls Neuronal Development by Regulating Camk2α Expression Independent of RIG-I Signaling
    Cell Reports, Oct 20, 2020
    Summary Eukaryotic mRNAs are 5′ end capped with a 7-methylguanosine, which is important for processing and translation of mRNAs. ......
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  • CPEB2-activated PDGFRα mRNA translation contributes to myofibroblast proliferation and pulmonary alveologenesis
    Journal of Biomedical Science, Apr 15, 2020
    Background Alveologenesis is the final stage of lung development to form air-exchanging units between alveoli and blood vessels. Genetic ......
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  • CPEB2‐dependent translation of long 3′‐UTR Ucp1 mRNA promotes thermogenesis in brown adipose tissue
    EMBO J, Sep 03, 2018
    Expression of mitochondrial proton transporter uncoupling protein 1 (UCP1) in brown adipose tissue (BAT) is essential for mammalian thermoge ......
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