Dr. Jou, Yuh-Shan 周玉山 博士



  • PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular translocations and tumor progression
    Nature Communications, Dec 16, 2019
    Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide due to metastasis. Paraspeckle component 1 (PSPC1) upregulation h ......
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  • A New Switch for TGFβ in Cancer
    Cancer Research, Jul 12, 2019
    The TGFβ cytokine plays dichotomous roles during tumor progression. In normal and premalignant cancer cells, the TGFβ signaling pa ......
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  • PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis
    Nature cell biology, Mar 28, 2018
    Activation of metastatic reprogramming is critical for tumour metastasis. However, more detailed knowledge of the underlying mechanism is ne ......
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  • EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma
    Oncotarget, Jan 11, 2018
    Targeting tumor angiogenesis is a common strategy against human hepatocellular carcinoma (HCC). However, identification of molecular targets ......
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  • Pyrimidine metabolic rate limiting enzymes in poorly-differentiated hepatocellular carcinoma are signature genes of cancer stemness and associated with poor prognosis
    Oncotarget, Sep 08, 2017
    Cellular metabolism of cancer cell is generally recognized to provide energy for facilitating tumor growth, but little is known about the ab ......
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List of Highlights