Dr. Shieh, Sheau-Yann
Research Fellow
- 02-26523916 (Lab) (Room No: N347)
- 02-27829143 (Fax)
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Specialty:
- Cancer Cell Biology
- Cell Cycle Signaling
Education and Positions:
Ph.D. Baylor College of Medicine Post-doc:Columbia University
Highlight Detail
The cell cycle checkpoint kinase CHK2 mediates DNA damage-induced stabilization of TTK/hMps1.
Dr. Shieh, Sheau-Yann
Oncogene, Jan 19, 2009Cell cycle progression is monitored constantly to ensure faithful passage of genetic codes and genome stability. We have demonstrated previously that, upon DNA damage, TTK/hMps1 activates the checkpoint kinase CHK2 by phosphorylating CHK2 at Thr68.