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Claudin-1 is a Metastasis Suppressor and Correlates with Clinical Outcome in Lung Adenocarcinoma.
Am. J. Respir. Crit. Care Med., Sep 11, 2008Rationale: Claudin-1(CLDN1), a key component of tight junction complexes, was down-regulated in human lung adenocarcinomas. Objectives: To investigate the clinical significance of CLDN1 expression in lung adenocarcinoma patients and its role in cancer invasion and metastasis.
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