Dr. Shih, Chiaho
施嘉和 博士
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Hepatitis B virus virion secretion is a CRM1-spike-mediated late event
Journal of Biomedical Science Jun 21, 2022
Background: Hepatitis B virus (HBV) is a major human pathogen worldwide. To date, there is no curative tr ......
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CRM1-spike-mediated nuclear export of hepatitis B virus encapsidated viral RNA
Cell Reports Mar 08, 2022
Hepatitis B virus (HBV) is a global pathogen. We report here that the cellular CRM1 machinery can mediate nucl ......
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Persistence of Hepatitis B Virus DNA and the Tempos between Virion Secretion and Genome Maturation in a Mouse Model
Journal of Virology Oct 29, 2019
Hepatitis B virus (HBV) core protein (HBc) accumulates frequent mutations in natural infection. Wild-type HBV is known to secrete predominan ......
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Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model
Journal of Biomedical Science Nov 11, 2019
Background Enterovirus 71 (EV71 or EV-A71) was first identified in California about half a century ago. In recent years, outbreaks of EV- ......
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Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model
Scientific Reports Jul 31, 2019
Severe infection with the re-emerging enterovirus 71 (EV71 or EV-A71) can cause cardiopulmonary failure. However, in patients’ heart a ......
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List of Highlights
文件紀錄
Hepatitis B virus virion secretion is a CRM1-spike-mediated late event
Journal of Biomedical Science Jun 21, 2022
CRM1-spike-mediated nuclear export of hepatitis B virus encapsidated viral RNA
Cell Reports Mar 08, 2022
Persistence of Hepatitis B Virus DNA and the Tempos between Virion Secretion and Genome Maturation in a Mouse Model
Journal of Virology Oct 29, 2019
Hypoxia and therapeutic treatment of EV-A71 with an immune modulator TLR7 agonist in a new immunocompetent mouse model
Journal of Biomedical Science Nov 11, 2019
Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model
Scientific Reports Jul 31, 2019
Hepatitis B Virus
Trends in microbiology Feb 27, 2018
Heparin at physiological concentration can enhance PEG-free in vitro infection with human hepatitis B virus
Scientific Reports Oct 31, 2017
HBV maintains electrostatic homeostasis by modulating negative charges from phosphoserine and encapsidated nucleic acids
Scientific Reports Dec 13, 2016
MicroRNA-130a can inhibit hepatitis B virus replication via targeting PGC1α and PPARγ.
RNA Jan 16, 2015
A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71
Scientific Reports Aug 08, 2016
Control and Eradication Strategies of Hepatitis B Virus
Trends in Microbiology Jun 07, 2016
The Dual Role of an ESCRT-0 Component HGS in HBV Transcription and Naked Capsid Secretion.
PLoS Pathog. Oct 02, 2015
Immunodeficient Mouse Models with Different Disease Profiles by in vivo Infection with the Same Clinical Isolate of Enterovirus 71.
J Virol. Aug 20, 2014
Nucleic Acid Chaperone Activity Associated with the ARD Domain of Human Hepatitis B Virus Core Protein.
J Virol. Dec 18, 2013
Identification of a Novel Antimicrobial Peptide from Human Hepatitis B Virus Core Protein Arginine-Rich Domain (ARD).
PLOS Pathogens. Jun 13, 2013
Nuclear Export and Import of Human Hepatitis B Virus Capsid Protein and Particles.
PLoS Pathogens Oct 28, 2010
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