Dr. Shen, Chen-Yang 沈志陽博士 HIGHLIGHT DETAIL 重要成果詳細內容

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重要成果詳細內容

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan.

N Engl J Med., Mar 24, 2011

Carbamazepine, an anticonvulsant and a mood-stabilizing drug, is the main cause of the Stevens–Johnson syndrome (SJS) and its related disease, toxic epidermal necrolysis (TEN), in Southeast Asian countries. Carbamazepine-induced SJS–TEN is strongly associated with the HLA-B*1502 allele. We sought to prevent carbamazepine-induced SJS–TEN by using HLA-B*1502 screening to prospectively identify subjects at genetic risk for the condition.

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HIGHLIGHT DETAIL重要成果詳細內容

Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan.

List of Highlights文件紀錄

HIGHLIGHT DETAIL
重要成果詳細內容

List of Highlights
文件紀錄