Dr. Shen, Chen-Yang 沈志陽 博士

List of Highlights
文件紀錄

• Inhibitory Effects of Ursolic Acid on the Stemness and Progression of Human Breast Cancer Cells by Modulating Argonaute-2

  International Journal of Molecular Sciences Dec 26, 2022

• Genome-wide association study identifies genetic risk loci for adiposity in a Taiwanese population

  PLOS Genetics Jan 20, 2022

• A common variant in 11q23.3 associated with hyperlipidemia is mediated by the binding and regulation of GATA4

  npj Genomic Medicine Jan 19, 2022

• Body mass index and type 2 diabetes and breast cancer survival: a Mendelian randomization study

  American Journal of Cancer Research Aug 30, 2021

• Rare variants discovery by extensive whole-genome sequencing of the Han Chinese population in Taiwan: Applications to cardiovascular medicine.

  J Adv Res. Jul 01, 2021

• MiR-139 Modulates Cancer Stem Cell Function of Human Breast Cancer through Targeting CXCR4

  Cancers May 25, 2021

• Detecting Genetic Ancestry and Adaptation in the Taiwanese Han People

  Molecular Biology and Evolution Dec 18, 2020

• Tumorigenic and Metastatic Role of CD44−/low/CD24−/low Cells in Luminal Breast Cancer

  Cancers May 14, 2020

• A Functional Variant Near XCL1 Gene Improves Breast Cancer Survival via Promoting Cancer Immunity

  International Journal of Cancer Jan 06, 2020

• The Causal Relationship of Circulating Triglycerides and Glycated Hemoglobin: A Mendelian Randomization Study

  Journal of Clinical Endocrinology & Metabolism Nov 30, 2019

• Increased Cellular Levels of MicroRNA-9 and MicroRNA-221 Correlate with Cancer Stemness and Predict Poor Outcome in Human Breast Cancer

  Cellular Physiology and Biochemistry Aug 15, 2018

• SUMOylation of XRCC1 activated by poly(ADP-ribosyl)ation regulates DNA repair

  Human Molecular Genetics Apr 16, 2018

• B-Myb Induces APOBEC3B Expression Leading to Somatic Mutation in Multiple Cancers

  Scientific Reports Mar 09, 2017

• Foxo3a-mediated overexpression of microRNA-622 suppresses tumor metastasis by repressing hypoxia-inducible factor-1α in ERK-responsive lung cancer.

  Oncotarget. Oct 23, 2015

• Use of HLA-B*58:01 genotyping to prevent allopurinol induced severe cutaneous adverse reactions in Taiwan: national prospective cohort study.

  BMJ. Sep 23, 2015

• MicroRNA-30a increases tight junction protein expression to suppress the epithelial-mesenchymal transition and metastasis by targeting Slug in breast cancer.

  Oncotarget Feb 24, 2016

• FGFR2 regulates Mre11 expression and double-strand break repair via the MEK-ERK-POU1F1 pathway in breast tumorigenesis.

  Hum Mol Genet. May 18, 2015

• A novel estrogen receptor-microRNA 190a-PAR-1-pathway regulates breast cancer progression, a finding initially suggested by genome-wide analysis of loci associated with lymph-node metastasis.

  Hum Mol Genet. Sep 22, 2013

• Carbamazepine-Induced Toxic Effects and HLA-B*1502 Screening in Taiwan.

  N Engl J Med. Mar 24, 2011

• Diverse Associations between ESR1 Polymorphism and Breast Cancer Development and Progression.

  Clinical Cancer Research Jun 22, 2010

• Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair.

  The EMBO Journal Oct 30, 2008

• Genetic Variation in the Premature Aging Gene WRN: A Case-Control Study on Breast Cancer usceptibility.

  Cancer Epidemiology Biomarkers & Prevention. Feb 01, 2007

• Breast Cancer Risk Associated with Genotypic Polymorphism of the Mitotic Checkpoint Genes: a ultigenic Study on Cancer Susceptibility.

  Carcinogenesis. Jan 08, 2007

• Ataxia Telangiectasia Mutated and Checkpoint Kinase 2 Regulate BRCA1 to Promote the Fidelity of DNA End-Joining.

  Cancer Research. Feb 01, 2006