Dr. Shen, Chen-Yang
Distinguished Research Fellow
- 02-27899036 (Lab) (Room No: N143)
- 02-27823047 (Fax)
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Specialty:
- Molecular Epidemiology
- Cancer Genetics
- Personalized Medicine
Education and Positions:
Ph.D. Univ. of North Carolina at Chapel Hill
Highlight Detail
Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair.
Dr. Shen, Chen-Yang
The EMBO Journal, Oct 30, 2008The DNA damage response (DDR) has an essential function in maintaining genomic stability. Ataxia telangiectasia-mutated (ATM)-checkpoint kinase 2 (Chk2) and ATM- and Rad3-related (ATR)-Chk1, triggered, respectively, by DNA double-strand breaks and blocked replication forks