Dr. Hsieh, Patrick Ching-Ho
Distinguished Research Fellow
Division Chief
- 02-27899170 (Lab) (Room No: N417)
- 02-27858594 (Fax)
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Specialty:
- Stem cells and regenerative medicine
- Nanoscience and nanomedicine
- Translational Research
Education and Positions:
M.D. Kaohsiung Medical College
Ph.D. University of Washington, Seattle (Bioengineering)
Highlight Detail
Instructive Nanofiber Scaffolds with VEGF Create a Microenvironment for Arteriogenesis and Cardiac Repair.
Dr. Hsieh, Patrick Ching-Ho
Sci Transl Med., Aug 08, 2012Angiogenic therapy is a promising approach for tissue repair and regeneration. However, recent clinical trials with protein delivery or gene therapy to promote angiogenesis have failed to provide therapeutic effects. A key factor for achieving effective revascularization is the durability of the microvasculature and the formation of new arterial vessels. Accordingly, we carried out experiments to test whether intramyocardial injection of self-assembling peptide nanofibers (NFs) combined with vascular endothelial growth factor (VEGF) could create an intramyocardial microenvironment