Dr. Liu, Fu-Tong 劉扶東 博士

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  • Galectin-3 promotes noncanonical inflammasome activation through intracellular binding to lipopolysaccharide glycans
    PNAS, Jul 27, 2021
        Cytosolic lipopolysaccharides (LPSs) bind directly to caspase-4/5/11 through their lipid A moiety, inducing inflammatory ......
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  • Indispensable role of Galectin-3 in promoting quiescence of hematopoietic stem cells.
    Nat Commun, Apr 09, 2021
    Hematopoietic stem cells (HSCs) in adult bone marrow (BM) are usually maintained in a state of quiescence. The cellular mechanism coordinati ......
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  • Intracellular galectins sense cytosolically exposed glycans as danger and mediate cellular responses
    Journal of Biomedical Science, Mar 04, 2021
        Galectins are animal lectins that recognize carbohydrates and play important roles in maintaining cellular homeostasis. ......
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  • Galectin-8 Is Upregulated in Keratinocytes by IL-17A and Promotes Proliferation by Regulating Mitosis in Psoriasis.
    J Invest Dermatol, Mar 01, 2021
    Psoriasis is a chronic inflammatory skin disease that develops under the influence of the IL-23/T helper 17 cell axis and is characterized b ......
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  • FUT8 Remodeling of EGFR Regulates Epidermal Keratinocyte Proliferation during Psoriasis Development.
    J Invest Dermatol, Mar 01, 2021
    α-(1,6)-fucosyltransferase 8 (FUT8) is implicated in the pathogenesis of several malignancies, but its role in psoriasis is poorly und ......
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