Dr. Cheng, Yang
Assistant Research Fellow
- 2789-9097 (Lab) (Room No: N401)
- 2652-3966 (Office)
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Specialty:
- Human T cell biology, virus-specific memory T cells
- Highly multiplexed combinatorial pMHC tetramer staining
- Single-cell multi-omics
- T cell receptor
- High-dimensional analysis
Education and Positions:
M.Sc., University College London
Ph.D., Nanyang Technological University – A*STAR joint program
Postdoc Fellow, Singapore Immunology Network, A*STAR
Senior Research Scientist, Massachusetts General Hospital, Harvard Medical School
Highlight Detail
Multifactorial heterogeneity of virus-specific T cells and association with the progression of human chronic hepatitis B infection
Dr. Cheng, Yang
Sci Immunol., Feb 08, 2019Associations between chronic antigen stimulation, T cell dysfunction, and the expression of various inhibitory receptors are well characterized in several mouse and human systems. During chronic hepatitis B virus (HBV) infection (CHB), T cell responses are blunted with low frequencies of virus-specific T cells observed, making these parameters difficult to study.