PUBLICATIONS
研究論文
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1. Lee JD, Paulo JA, Posey RR, Mugoni V, Kong NR, Cheloni G, (Lee YR), Slack FJ, Tenen DG, Clohessy JG, Gygi SP, Pandolfi PP Dual DNA and protein tagging of open chromatin unveils dynamics of epigenomic landscapes in leukemia. Nature methods 18(3), 293–302 (2021) [JCR] [WOS] -
2. Kishikawa T, Higuchi H, Wang L, Panch N, Maymi V, Best S, Lee S, Notoya G, Toker A, Matesic LE, Wulf GM, Wei W, Otsuka M, Koike K, Clohessy JG, Lee YR, Pandolfi PP WWP1 inactivation enhances efficacy of PI3K inhibitors while suppressing their toxicities in breast cancer models. The Journal of clinical investigation 131(24), e140436-e140436 (2021) [JCR] [WOS] -
3. Lee YR, Pandolfi PP PTEN Mouse Models of Cancer Initiation and Progression. Cold Spring Harbor perspectives in medicine 10(2), a037283-a037283 (2020) [JCR] [WOS] -
4. Lee YR, Yehia L, Kishikawa T, Ni Y, Leach B, Zhang J, Panch N, Liu J, Wei W, Eng C, Pandolfi PP WWP1 Gain-of-Function Inactivation of PTEN in Cancer Predisposition. The New England journal of medicine 382(22), 2103-2116 (2020) [JCR] [WOS] -
5. Zhang J#, Lee YR#, Dang F, Gan W, Menon AV, Katon JM, Hsu CH, Asara JM, Tibarewal P, Leslie NR, Shi Y, Pandolfi PP, Wei W. #Co-first author PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. CANCER DISCOVERY 9(9), 1306-1323 (2019) [JCR] [WOS] -
6. Lee YR, Chen M, Lee JD, Zhang J, Lin SY, Fu TM, Chen H, Ishikawa T, Chiang SY, Katon J, Zhang Y, Shulga YV, Bester AC, Fung J, Monteleone E, Wan L, Shen C, Hsu CH, Papa A, Clohessy JG, Teruya-Feldstein J, Jain S, Wu H, Matesic L, Chen RH, Wei W, Pandolfi PP Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science (New York, N.Y.) 364(6441), aau0159-aau0159 (2019) [JCR] [WOS] -
7. Chen M, Zhang J, Sampieri K, Clohessy JG, Mendez L, Gonzalez-Billalabeitia E, Liu XS, Lee YR, Fung J, Katon JM, Menon AV, Webster KA, Ng C, Palumbieri MD, Diolombi MS, Breitkopf SB, Teruya-Feldstein J, Signoretti S, Bronson RT, Asara JM, Castillo-Martin M, Cordon-Cardo C, Pandolfi PP An aberrant SREBP-dependent lipogenic program promotes metastatic prostate cancer. Nature genetics 50(2), 206-218 (2018) [JCR] [WOS] -
8. Bester AC, Lee JD, Chavez A, Lee YR, Nachmani D, Vora S, Victor J, Sauvageau M, Monteleone E, Rinn JL, Provero P, Church GM, Clohessy JG, Pandolfi PP An Integrated Genome-wide CRISPRa Approach to Functionalize lncRNAs in Drug Resistance. Cell 173(3), 649-664.e20 (2018) [JCR] [WOS] -
9. Lee YR, Chen M, Pandolfi PP The functions and regulation of the PTEN tumour suppressor: new modes and prospects. Nature reviews. Molecular cell biology 19(9), 547-562 (2018) [JCR] [WOS] -
10. Yuan WC#, Lee YR#, Lin SY, Chang LY, Tan YP, Hung CC, Kuo JC, Liu CH, Lin MY, Xu M, Chen ZJ, Chen RH. #Co-first author K33-Linked Polyubiquitination of Coronin 7 by Cul3-KLHL20 Ubiquitin E3 Ligase Regulates Protein Trafficking. Molecular cell 54(4), 586-600 (2014) [JCR] [WOS]
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