Academician Kwok was elected as a 2020 Fellow of the Biological Sciences Section, the American Association for the Advancement of Science (AAAS) for his “distinguished contributions to the development of human genomic technologies for assaying genome variation in all forms, and genome discoveries for human disease”.
The extracellular microenvironment provides the biochemical signals that control cell behavior and coordinate developmental and physiological processes. Any imbalance of such delicate regulation can considerably affect development and homeostasis. A research team composed of Dr. Ruey-Bing Yang (Research Fellow of Academia Sinica) and Dr. Yuh-Charn Lin (Research Scholar) of the Institute of Biomedical Sciences identified …(Read More)
Lung cancer is the leading cause of cancer death in Taiwan and the world, and its treatment has always been a topic of concern in the country. A research team composed of Drs. Pan-Chyr Yang (Academician of Academia Sinica), Shu-Ping Wang (Assistant Research Fellow) and Chia-Sing Lu (Postdoctoral Fellow) of the Institute of Biomedical Sciences, found that the chemotherapeutic agent …(Read More)
Academia Sinica Vice President Dr. Fu-Tong Liu is a pioneer and leader in the field of galectin research. Not only was he the discoverer of now well-known galectin-3, he also found that different galectins play very important functions in different diseases, and different galectins have the potential to become targets for the treatment of different diseases. …(Read More)
As is well known, psychological stress can result in psychiatric disorders, such as depression and anxiety. But do you know that repeated exposure to psychological stress can also cause chronic physical pain? Dr. Chih-Cheng Chen, research fellow in the Institute of Biomedical Sciences, Academia Sinica …(Read More)
Galectin-9 is a carbohydrate-binding protein and is a risk factor for inflammatory Crohn’s disease in the small intestine. Our research reveal N-glycosylation of lysosomal membrane proteins (Lamp2) in lysosomes of gut Paneth cells provides binding sites for galectin-9. The galectin-9-Lamp2 interaction not only stabilizes lysosomes but also maintains functionality of autophagy, which …(Read More)