細胞株鑑定的關鍵應用
Applications of Human Cell Line Identification
服務簡介
細胞培養是生命科學研究的重要基礎,但細胞株污染和錯誤標記問題常導致實驗結果不可靠,甚至影響研究發表。為解決此問題,我們提供基於短串聯重複序列 (Short Tandem Repeat, STR) 的人類細胞株鑑定服務,協助確認細胞來源,提升實驗可信度,同時符合期刊投稿與研究審查的要求。
適用情境
建議在以下情況進行細胞株鑑定,以提升研究準確性與可信度:
- 初次獲得細胞株
在取得新細胞株或建立新分離細胞株時,鑑定其基因型,確保細胞來源正確無誤。
- 防止交叉污染
定期檢測細胞株是否受到污染,確保實驗結果的可靠性。
- 保障遺傳穩定性
檢測細胞株的遺傳變化,了解其穩定性,避免因基因組漂變影響實驗結果。
- 提高實驗可重複性
鑑定細胞株身份,增強實驗的可重複性與研究成果的可信度。
- 實驗結果異常
當細胞形態異常或數據無法重現時,檢查細胞株是否被污染或標記錯誤。
- 期刊投稿或研究審查
確保符合國際期刊及資助機構的合規要求,提升投稿或審查通過率。
Service Overview
Cell culture is an essential tool in biological research, but issues like contamination or misidentification of cell lines can undermine the reliability of your experimental results. To address this challenge, we offer a Human Cell Line Authentication (CLA) Service based on Short Tandem Repeat (STR) analysis. This service ensures that your cell lines are correctly identified, helping to improve the quality of your research and meet the requirements for journal submissions and grant applications.
Recommended Use Cases
Cell line authentication is recommended in the following situations to ensure research accuracy and credibility:
- When acquiring new cell lines
Authenticate newly obtained or established cell lines to confirm their genetic identity and ensure the accuracy of their origin.
- To prevent cross-contamination
Regularly check for cross-contamination to maintain the reliability of experimental results.
- To ensure genetic stability
Monitor genetic variations in cell lines to assess their stability and avoid potential risks to experimental outcomes.
- To improve experimental reproducibility
Confirming cell line identity enhances reproducibility and strengthens the reliability of research findings.
- In cases of abnormal experimental results
Investigate contamination or misidentification when cells exhibit abnormal morphology or experimental data cannot be reproduced.
- For journal submissions or research reviews
Ensure compliance with international journal and funding agency requirements to improve the chances of successful submission or review approval.