陳建璋 博士

Quantitative phosphoproteomic study of pressure-overloaded mouse heart reveals dynamin-related protein 1 as a modulator of cardiac hypertrophy.

Mol Cell Proteomics., Jul 23, 2013

Pressure-overload stress to the heart causes pathological cardiac hypertrophy, which increases the risk of cardiac morbidity and mortality. ......

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陳金榜 博士

Structural Basis of a Physical Blockage Mechanism for the Interaction of Response Regulator PmrA with Connector Protein PmrD from Klebsiella Pneumoniae.

J Biol Chem., Jul 16, 2013

In bacteria, the two-component system (TCS) is the most prevalent for sensing and transducing environmental signals into the cell. The PmrA- ......

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唐堂 博士

CEP120 interacts with CPAP and positively regulates centriole elongation.

JCB., Jul 15, 2013

Centriole duplication begins with the formation of a single procentriole next to a preexisting centriole. CPAP (centrosomal protein 4.1&ndas ......

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施修明 博士

HIC1 interacts with and modulates the activity of STAT3.

Cell Cycle., Jun 21, 2013

Abstract: HIC1 (hypermethylated in cancer 1) is a tumor suppressor gene, expression of which is frequently suppressed in human cancers. Very ......

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施嘉和 博士

Identification of a Novel Antimicrobial Peptide from Human Hepatitis B Virus Core Protein Arginine-Rich Domain (ARD).

PLOS Pathogens., Jun 13, 2013

The rise of multidrug-resistant (MDR) pathogens causes an increasing challenge to public health. Antimicrobial peptides are considered a pos ......

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張程 博士

Visualization of rodent brain tumor angiogenesis and effects of antiangiogenic treatment using 3D ΔR2-μMRA.

Angiogenesis., Jun 05, 2013

Understanding of structural and functional characteristics of the vascular microenvironment in gliomas and the impact of antiangiogenic trea ......

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張程 博士

Hyperglycemia Exacerbates Intracerebral Hemorrhage via the Downregulation of Aquaporin-4.

Stroke., Jun 01, 2013

Intracerebral hemorrhage (ICH) is associated with high mortality and neurological deficits, and concurrent hyperglycemia usually worsens cli ......

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陳儀莊 博士

Lack of Type VI Adenylyl Cyclase (AC6) Leads to Abnormal Sympathetic Tone in Neonatal Mice.

Exp Neurol., May 28, 2013

Visceral functions are regulated by a basal sympathetic nerve discharge (SND), also known as 'sympathetic tone'. We demonstrate here ......

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謝清河 博士

Functionalized Nanoparticles Provide Early Cardioprotection after Acute Myocardial Infarction.

J Control Release, May 09, 2013

Recent developments in nanotechnology have created considerable potential toward diagnosis and cancer therapy. In contrast, the use of nanot ......

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林小喬 博士

Differential Role of the Protein Matrix on the Binding of a Catalytic Aspartate to Mg2+ vs Ca2+: Application to Ribonuclease H.

J Am Chem Soc., Apr 23, 2013

Divalent metal cations are essential cofactors for many enzyme functions. Although Mg2+ is the native cofactor in many enzymes such as ribon ......

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