Dr. Lin, Yi-Ling
Ebselen alleviates testicular pathology in mice with Zika virus infection and prevents its sexual transmission
PLoS Pathogens, Feb 15, 2018
Despite the low case fatality, Zika virus (ZIKV) infection has been associated with microcephaly in infants and Guillain-Barré syndro ......
Dr. Chang, Yi-Cheng
Subclinical and overt hypothyroidism is associated with reduced glomerular filtration rate and proteinuria: a large cross-sectional population study
Scientific Reports, Feb 01, 2018
Subclinical hypothyroidism has been associated with dyslipidemia, hypertension, and increased risk of coronary artery disease. However, limi ......
Dr. Pan, Wen-Harn
A Two-Stage Whole-Genome Gene Expression Association Study of Young-Onset Hypertension in Han Chinese Population of Taiwan
Scientific Reports, Jan 29, 2018
Hypertension is an important public health problem in the world. Since the intermediate position of the gene expression between genotype and ......
Dr. Liu, Fu-Tong
Galectin-3 enhances avian H5N1 influenza A virus–induced pulmonary inflammation by promoting NLRP3 inflammasome activation
The American Journal of Pathology, Jan 20, 2018
Highly pathogenic avian influenza A H5N1 virus causes pneumonia and acute respiratory distress syndrome in humans. Virus-induced excessive i ......
Dr. Chen, Chien-Chang
Spinal protein kinase C/extracellular signal-regulated kinase signal pathway mediates hyperalgesia priming
PAIN, Jan 18, 2018
Chronic pain can be initiated by one or more acute stimulations to sensitize neurons into the primed state. In the primed state, the basal n ......
Dr. Tang, Tang K.
Myosin-Va is required for preciliary vesicle transportation to the mother centriole during ciliogenesis
Nature Cell Biology, Jan 15, 2018
Primary cilia play essential roles in signal transduction and development. The docking of preciliary vesicles at the distal appendages of a ......
Dr. Jou, Yuh-Shan
EIF3C-enhanced exosome secretion promotes angiogenesis and tumorigenesis of human hepatocellular carcinoma
Oncotarget, Jan 11, 2018
Targeting tumor angiogenesis is a common strategy against human hepatocellular carcinoma (HCC). However, identification of molecular targets ......
Dr. Chern, Yijuang
GSK3β negatively regulates TRAX, a scaffold protein implicated in mental disorders, for NHEJ-mediated DNA repair in neurons
Molecular Psychiatry, Jan 03, 2018
Translin-associated protein X (TRAX) is a scaffold protein with various functions and has been associated with mental illnesses, including s ......