Dr. Kwok , Pui-Yan

Towards a reference genome that captures global genetic diversity

Nature Communications Oct 30, 2020

Abstract The current human reference genome is predominantly derived from a single individual and it does not adequately reflect human ......

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Dr. Chang , Yi-Cheng

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

Inherited causes of clonal haematopoiesis in 97,691 whole genomes Oct 14, 2020

Age is the dominant risk factor for most chronic human diseases, but the mechanisms through which ageing confers this risk are largely unkno ......

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Dr. Lin , Wen-chang

Top-ranked expressed gene transcripts of human protein-coding genes investigated with GTEx dataset

Scientific Reports Oct 01, 2020

Abstract With considerable accumulation of RNA-Seq transcriptome data, we have extended our understanding about protein-coding gene trans ......

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Dr. Chang , Yi-Cheng

Genome-wide association study for circulating fibroblast growth factor 21 and 23

Genome-wide association study for circulating fibroblast growth factor 21 and 23 Sep 03, 2020

Fibroblast growth factors (FGFs) 21 and 23 are recently identified hormones regulating metabolism of glucose, lipid, phosphate and vitamin D ......

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Dr. Lee , Yungling Leo

FUT8 remodeling of EGFR regulates epidermal keratinocyte proliferation during psoriasis development

Journal of Investigative Dermatology Sep 02, 2020

Abstract α-(1,6)-fucosyltransferase (FUT8) is implicated in the pathogenesis of several malignancies, but its role in psoriasis i ......

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Dr. Chang , Yi-Cheng

The Effects of Bariatric Surgery on Renal, Neurological, and Ophthalmic Complications in Patients with Type 2 Diabetes: the Taiwan Diabesity Study

The Effects of Bariatric Surgery on Renal, Neurological, and Ophthalmic Complications in Patients with Type 2 Diabetes: the Taiwan Diabesity Study Jul 18, 2020

After 2 years of follow-up, patients with type 2 diabetes receiving bariatric surgery had greater reduction in BMI, HbA1c, and urine albumin ......

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Dr. Lee , Yungling Leo

CEACAM3 Decreases Asthma Exacerbations and Modulates Respiratory Syncytial Virus Latent Infection in Children

Thorax Jun 30, 2020

Abstract Background: Respiratory syncytial virus (RSV) is associated with childhood asthma. Nevertheless, not all children exposed to ......

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Dr. Shen , Chen-Yang

Tumorigenic and Metastatic Role of CD44−/low/CD24−/low Cells in Luminal Breast Cancer

Cancers May 14, 2020

Abstract Cells with high CD44 but low CD24 expression (CD44high/CD24-/low) and high aldehyde dehydrogenase activity (ALDHbr) are widely ......

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Dr. Chang , Yi-Cheng

Stratified risks of infection-related hospitalization in patients with chronic kidney disease - A prospective cohort study

Stratified risks of infection-related hospitalization in patients with chronic kidney disease - A prospective cohort study Mar 11, 2020

Patients with chronic kidney disease (CKD) are at high risk of infection, but whether the risks are attenuated in different patient groups r ......

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Dr. Shen , Chen-Yang

A Functional Variant Near XCL1 Gene Improves Breast Cancer Survival via Promoting Cancer Immunity

International Journal of Cancer Jan 06, 2020

Most genome‐wide association studies (GWASs) identify genetic variants for breast cancer occurrence. In contrast, few are for recurrence and ......

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