Dr. Liao , Fang

Interferon-stimulated gene ISG12b2 is localized to the inner mitochondrial membrane and mediates virus-induced cell death.

Cell Death Differ. Dec 10, 2010

Interferons (IFNs) are crucial for host defence against viruses. Many IFN-stimulated genes (ISGs) induced by viral infection exert antiviral ......

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Dr. Chen , Steve S.-L.

Activation of the unfolded protein response and autophagy after hepatitis C virus infection suppresses innate antiviral immunity in vitro.

J Clin Invest. Dec 06, 2010

Hepatitis C virus (HCV) is a major cause of chronic liver disease, with more than 170 million infected individuals worldwide . In 50%– ......

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Dr. Shih , Chiaho

Nuclear Export and Import of Human Hepatitis B Virus Capsid Protein and Particles.

PLoS Pathogens Oct 28, 2010

It remains unclear what determines the subcellular localization of hepatitis B virus (HBV) core protein (HBc) and particles. To address this ......

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Dr. Shih , Hsiu-Ming

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.

J Cell Biol. Jun 21, 2010

Mitotic spindles play essential roles in chromosome congression and segregation during mitosis. Aurora A regulates spindle assembly in part ......

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