Dr. Shih , Hsiu-Ming

The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability.

Oncogene Dec 03, 2012

Acute promyelocytic leukemia (APL) is predominantly characterized by chromosomal translocations between the retinoic acid receptor, alpha (R ......

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Dr. Liu , Fu-Tong

Galectin-3 Regulates Intracellular Trafficking of EGFR through Alix and Promotes Keratinocyte Migration.

Journal of Investigative Dermatology Dec 01, 2012

The EGFR-mediated signaling pathways are important in a variety of cellular processes, including cell migration and wound re-epithelializati ......

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Dr. Lin , Yi-Ling

Dengue Virus Targets the Adaptor Protein MITA to Subvert Host Innate Immunity.

PLoS Pathogens Jun 28, 2012

Dengue is one of the most important arboviral diseases caused by infection of four serotypes of dengue virus (DEN). We found that activation ......

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Dr. Kannagi , Reiji

Transcription factors c-Myc and CDX2 mediate E-selectin ligand expression in colon cancer cells undergoing EGF/bFGF-induced epithelial–mesenchymal transition

PNAS May 15, 2012

Sialyl Lewis x (sLex) and sialyl Lewis a (sLea)   glycans are expressed on highly metastatic colon cancer cells. They   promote ex ......

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Dr. Tao , Mi-Hua

Cancer Immunotherapy Using a Membrane-bound Interleukin-12 With B7-1 Transmembrane and Cytoplasmic Domains.

Molecular Therapy Feb 14, 2012

Interleukin-12 (IL-12) has potent antitumor activity, but its clinical application is limited by severe systemic toxicity, which might be al ......

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