Dr. Shih , Chiaho Nucleic Acid Chaperone Activity Associated with the ARD Domain of Human Hepatitis B Virus Core Protein.
J Virol. Dec 18, 2013Hepatitis B virus (HBV) DNA replication occurs within the HBV icosahedral core particles. HBV core protein (HBc) contains an arginine-rich d ......
detail
Dr. Lin , Yi-Ling Ubiquitin-Specific Protease 13 Regulates IFN Signaling by Stabilizing STAT1.
J Immunol. Aug 12, 2013The IFN immune system comprises type I, II, and III IFNs, signals through the JAK-STAT pathway, and plays central roles in host defense agai ......
detail
Dr. Liao , Fang Melanoma Differentiation–Associated Gene 5 Senses Hepatitis B Virus and Activates Innate Immune Signaling to Suppress Virus Replication.
J Immunol. Aug 07, 2013Retinoic acid–inducible gene-I (RIG-I) and melanoma differentiation–associated gene 5 (MDA5) belong to the RIG-I–like rece ......
detail
Dr. Shih , Hsiu-Ming HIC1 interacts with and modulates the activity of STAT3.
Cell Cycle. Jun 21, 2013Abstract: HIC1 (hypermethylated in cancer 1) is a tumor suppressor gene, expression of which is frequently suppressed in human cancers. Very ......
detail
Dr. Shih , Chiaho Identification of a Novel Antimicrobial Peptide from Human Hepatitis B Virus Core Protein Arginine-Rich Domain (ARD).
PLOS Pathogens. Jun 13, 2013The rise of multidrug-resistant (MDR) pathogens causes an increasing challenge to public health. Antimicrobial peptides are considered a pos ......
detail
Dr. Shih , Hsiu-Ming Ubc9 acetylation modulates distinct SUMO target modification and hypoxia response.
EMBO J. Feb 08, 2013While numerous small ubiquitin-like modifier (SUMO) conjugated substrates have been identified, very little is known about the cellular sign ......
detail
Dr. Lin , Yi-Ling MCPIP1 ribonuclease exhibits broad-spectrum antiviral effects through viral RNA binding and degradation.
Nucleic Acids Res. Jan 25, 2013Monocyte chemoattractant protein 1-induced protein 1 (MCPIP1), belonging to the MCPIP family with highly conserved CCCH-type zinc finger and ......
detail| Record 1 to 7, total of 7 records |
