Epidemiology & Genetics
Neuroscience
Cardiovascular Research
Infectious Disease & Immunology
Cancer
Structural Biology
Research Highlights
Dr. Roffler, Steve R. Pharmaceutics, Dec 21, 2019
Both IgM and IgG Antibodies Against Polyethylene Glycol Can Alter the Biological Activity of M ......
Pre-existing antibodies that bind polyethylene glycol are present in about 40% of healthy individuals. It is currently unknown if pre-existing anti-polyethylene glycol (PEG) antibodies can alter the bioactivity of pegylated drugs with a sin ...... MORE
Dr. Jou, Yuh-Shan Nucleic Acids Research, Dec 19, 2019
Integrative analyses of noncoding RNAs reveal the potential mechanisms augmenting tumor malign ......
Precise noncoding RNA (ncRNA)-based network prediction is necessary to reveal ncRNA functions and pathological mechanisms. Here, we established a systemic pipeline to identify prognostic ncRNAs, predict their functions and explore their pat ...... MORE
Dr. Jou, Yuh-Shan Nature Communications, Dec 16, 2019
PSPC1-interchanged interactions with PTK6 and β-catenin synergize oncogenic subcellular transl ......
Hepatocellular carcinoma (HCC) is one of the most lethal cancers worldwide due to metastasis. Paraspeckle component 1 (PSPC1) upregulation has been identified as an HCC pro-metastatic activator associated with poor patient prognosis, but&nb ...... MORE
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