Epidemiology & Genetics
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Infectious Disease & Immunology
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Structural BiologyResearch Highlights
Dr. Yen, Jeffrey J.Y. Journal of Investigative Dermatology, Oct 25, 2019
Palmitoyl acyltransferase activity of ZDHHC13 regulates skin barrier development partly by con ......
Deficiency of the palmitoyl-acyl transferase ZDHHC13 compromises skin barrier permeability and renders mice susceptible to environmental bacterial infection and inflammatory dermatitis. It had been unclear how lack of ZDHHC13 proteins resul ...... MORE
Dr. Chang, Ya-Jen Allergy, Oct 17, 2019
Pulmonary IL‐33 orchestrates innate immune cells to mediate RSV‐evoked airway hyperreactivity ......
Background Respiratory syncytial virus (RSV) infection is epidemiologically linked to asthma. During RSV infection, IL‐33 is elevated and promotes immune cell activation, leading to the development of asthma. However, which immune cell ...... MORE
Dr. Lim, Carmay Accounts of Chemical Research, Sep 26, 2019
Free and Bound Therapeutic Lithium in Brain Signaling
Lithium, a first-line therapy for bipolar disorder, is effective in preventing suicide and new depressive/manic episodes. Yet, how this beguilingly simple monocation with only two electrons could yield such profound therapeutic effects rema ...... MORE
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