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Structural BiologyResearch Highlights
Dr. Hu, Che-Ming (Jack) Nano Letters, Mar 17, 2020
Synthetic Immunogenic Cell Death Mediated by Intracellular Delivery of STING Agonist Nanoshell ......
Many favorable anticancer treatments owe their success to the induction immunogenic cell death (ICD) in cancer cells, which results in the release of endogenous danger signals along with tumor antigens for effective priming of anticancer im ...... MORE
Dr. Li, Chia-Wei Cancer Research, Mar 10, 2020
Targeting glycosylated PD-1 induces potent anti-tumor immunity
Immunotherapies targeting programmed cell death protein 1 (PD-1) and programmed cell death 1 ligand 1 (PD-L1) immune checkpoints represent a major breakthrough in cancer treatment. PD-1 is an inhibitory receptor expressed on the surface of ...... MORE
Dr. Roffler, Steve R. ACS Nano, Mar 06, 2020
Premature Drug Release from Polyethylene Glycol (PEG)-Coated Liposomal Doxorubicin via Formati ......
Anti-polyethylene glycol (PEG) antibodies are present in many healthy individuals as well as in patients receiving polyethylene glycol-functionalized drugs. Antibodies against PEG-coated nanocarriers can accelerate their clearance, but thei ...... MORE
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