蔡作雍博士

退休研究員
中央研究院院士
  • 02-27899105
  • 02-27829224 (Fax)
Specialty:
  • Central cardiovascular Integration (CCI)
  • Central Integration of Defense Reactions
  • Non-cardiovascular Functions of CCI
Education and Positions:

  • M.D., Ph.D. Columbia Univ.

本實驗室研究延腦對生理功能的調控。除延腦的腹側部，我們發現延腦背部在維持血管張力，血壓上升及參與中腦防禦反應所引發之心血管作用中扮演重要的角色。以延腦背部為核心，我們探討它與其他神經核的關係。進一步證明，延腦尾端腹側部具有整合調控心血管與呼吸的機制及抗缺氧的能力。此外，延腦的心血管調控區，也混雜其他神經細胞具有調控呼吸、腸胃道及軀體系統反射的功能。所以，延腦藉由多重調控機制來維持生理恆定。

期刊 44 專書 0

  1. M. R. Wang, J. S. Kuo and C. Y. Chai Depressor and vocalized responses to carbachol on the visual cortex and dorsolateral and intermediate-lateral periaqueductal grey in cats 7th IBRO World Congress of Neuroscience, July 12-17, 2007 (book of abstracts) 347 (2007) [JCR] [WOS]
  2. C. Y. Yang, P. C. Tan, W. C. Wu, J. C. Hsu, L. C. See and C. Y. Chai Inhibitory Effects of Propofol on Neuron Firing Activities in the Rostral Ventrolateral Medulla Chin. J. Physiol 50, 251-257 (2007) [JCR] [WOS]
  3. W. C. Wu, J. P. Ueng and C. Y. Chai Effects of Asphyxia on Arterial Blood Pressure, Formation of Nitric Oxide in Medulla and Blood Parameters in the Cat Chin. J. Physiol 48, 51-56 (2005) [JCR] [WOS]
  4. Y. W. Cheng, M. C. Ku, C. M. Ho, C. Y. Chai and C. K. Su GABAB-Receptor- Mediated Suppression of Sympathetic Outflow from the Spinal Cord of Neonatal Rats J. Appl. Physiol 99, 1658-1667 (2005) [JCR] [WOS]
  5. W. C. Wu, M. R. Wang, C. Y. Yang, C. K. Su and C. Y. Chai Serotonin modulates glutamate action in the medulla to regulate cardiovascular functions in cats Chin J Physiol 48, 65-71 (2005) [JCR] [WOS]
  6. W .C. Wu, C.Y. Chai Nitric oxide release in the nucleus tractus solitarius during and after bilateral common carotid artery occlusion Clin Exp Pharmacol Physiol 31, 152-158 (2004) [JCR] [WOS]
  7. S. Y. Chen, C. Y. Chai Coexistence of neurons integrating urinary bladder activity and pelvic nerve activity in the same cardiovascular areas of the pontomedulla in cats Chin J Physiol 45, 41-50 (2002) [JCR] [WOS]
  8. W. C. Wu, Y. Wang, L. S. Kao, F. I. Tang and C. Y. Chai Nitric oxide reduces blood pressure in the nucleus tractus solitarius: a real time electrochemical study Brain Res Bull 57, 171-177 (2002) [JCR] [WOS]
  9. L. Z. Hong, J. S. Kuo, M. H. Yen and C. Y. Chai Dorsomedial medulla is more susceptible than rostral ventrolateral medulla to hypoxic insult in cats J Appl Physiol 90, 248-260 (2001) [JCR] [WOS]
  10. S. Y. Chen, S. P. Mao and C. Y. Chai Role of nitric oxide on pressor mechanisms within the dorsomedial and rostral ventrolateral medulla in anaesthetized cats Clin Exp Pharmacol Physiol 28, 155-163 (2001) [JCR] [WOS]
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