感染疾病與免疫學

  • 分析人類病原體（包括流感病毒、黃質病毒、冠狀病毒、B型肝炎病毒等）感染過程的特徵，為治療途徑提供進一步的訊息。
  • 透過細胞培養、動物模型以及先進的影像技術，闡明免疫相關疾病（例如: 氣喘、發炎性腸道症和COVID-19等）的致病機轉。
  • 推進疫苗和藥物技術，來預防和治療感染性疾病和免疫失調症。
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林宜玲
特聘研究員
Division Chief
Specialty
  • Molecular Virology
  • Viral Pathogenesis
  • Viral Immunology
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張雅貞
研究員
Specialty
  1. Allergy and asthma
  2. Innate immunity and mucosal immunology
  3. Immunopharmacology
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范盛娟
研究員
Specialty
  • Genetic Statistics
  • Genetic Epidemiology
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李永凌
研究員
Specialty

1. Adaptive Immunity

2. Omics and Precision Medicine

3. Antigen Presenting Cells

4. Vaccine Development

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陶秘華
研究員
Specialty
  • Viral and Cancer Immunology
  • Viral and Cancer Immunotherapy
  • Vaccine Development
  • Gene Therapy
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胡哲銘
長聘副研究員
Specialty

Biomaterials and Nanotechnology for Drug and Vaccine Development

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徐志文
長聘副研究員
Specialty

(Host defense & Mucosal immunity)

(Lysosome dysfunction)

(Colitis pathogenesis)

 

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陳英翰
助研究員
Specialty
  • Host-microbe interactions
  • Immunology
  • Microbiota
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鄭揚
助研究員
Specialty
  • Human T cell biology, virus-specific memory T cells
  • Highly multiplexed combinatorial pMHC tetramer staining
  • Single-cell multi-omics
  • T cell receptor
  • High-dimensional data analysis
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李彥莉
助研究員
Specialty

Virus-host interactions

Structural biology

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蔡松智
助研究員
Specialty

Epitranscriptomic RNA modifications

Virus-host interactions

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王宜萱
助研究員
Specialty

Cell biology of viral infections

Virus entry and egress

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陳煥源
研究副技師
Specialty
  • 發炎核心設施負責人
  • Galectins
  • Skin Inflammation
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張耀明
研究助技師
Specialty

Computational Biology

Transcriptome Analysis

Gene Regultory Network

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柯泰名
合聘助研究員
合聘
Specialty

Immunogenomics

Pharmacogenetics

Genomic medicine

- 感染疾病與免疫學 研究成果 -
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胡哲銘 博士
High-Affinity Superantigen-Based Trifunctional Immune Cell Engager Synergizes NK and T Cell Activation for Tumor Suppression
Advanced Science Jun 27, 2024

The development of immune cell engagers (ICEs) can be limited by logistical and functional restrictions associated with fusion protein desig ...

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蔡松智 博士
Epitranscriptomic cytidine methylation of the hepatitis B viral RNA is essential for viral reverse transcription and particle production
PNAS Jun 03, 2024

Epitranscriptomic RNA modifications have emerged as important regulators of the fate and function of viral RNAs. One prominent modification, ...

...
胡哲銘 博士
Overcoming the nutritional immunity by engineering iron-scavenging bacteria for cancer therapy
Elife May 15, 2024

Certain bacteria demonstrate the ability to target and colonize the tumor microenvironment, a characteristic that positions them as innovati ...

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范盛娟 博士
Unsupervised Clustering Identified Clinically Relevant Metabolic Syndrome Endotypes in UK and Taiwan Biobanks
iScience Apr 25, 2024

Metabolic syndrome (MetS) is a collection of cardiovascular risk factors; however, the high prevalence and heterogeneity impede effective cl ...

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張雅貞 博士
Staphylococcus aureus exacerbates dermal IL-33-ILC2 axis activation through evoking RIPK3/MLKL-mediated necroptosis of dry skin
JCI Insight Feb 06, 2024

Atopic dermatitis (AD) is a persistent skin disease typified by symptoms of dry skin and recurrent eczema. AD patients are at heightened ris ...

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胡哲銘 博士
Bacteria colonization in tumor microenvironment creates a favorable niche for immunogenic chemotherapy
EMBO Molecular Medicine Jan 15, 2024

The tumor microenvironment (TME) presents differential selective pressure (DSP) that favors the growth of cancer cells, and monovalent thera ...

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