Dr. Lin, Wan-Chen 's publons link picture Dr. Lin, Wan-Chen 's Twitter

林宛蓁博士

助研究員
  • 2789-9120 (Lab) (Room No: N221)
  • 2652-3039 (Office)
Specialty:
  • Chemical Biology
  • Optogenetics
  • Neurotransmitter Receptors and Ion Channels
Education and Positions:

  • Ph.D. Massachusetts Institute of Technology

    Postdoc. University of California, Berkeley

本實驗室為高度跨領域的研究團隊，致力於突破現有技術極限，解構神經傳導的細胞及分子網絡。我們結合化學、生物工程、生物物理、以及神經科學的概念與技術，發展創新的工具及方法，進而運用這些科技精準調控或探測複雜的神經傳導現象。我們已開發了一系列光遺傳/光藥理學工具，目前正建立各式實驗系統，將新工具應用於突觸可塑性、學習/記憶、以及疼痛的機制探討，並且持續開發新的工具及方法學。如欲進一步了解實驗室各項研究課題，請詳見英文版網頁。

我們歡迎有志從事跨領域生醫科學/神經科學/化學生物學的朋友們加入團隊，徵才詳情請參閱最新PDF版廣告(連結)。

期刊 8 專書 0

  1. (Lin Wan-Chen),* Tsai Ming-Chi, Rajappa Rajit, Kramer Richard H.* Design of a Highly Bistable Photoswitchable Tethered Ligand for Rapid and Sustained Manipulation of Neurotransmission Journal of the American Chemical Society 140(24), 7445-7448 (2018) [JCR] [WOS]
  2. (Lin Wan-Chen),* Kramer Richard H.* Light-Switchable Ion Channels and Receptors for Optogenetic Interrogation of Neuronal Signaling Bioconjugate Chemistry 29(4), 861-869 (2018) [JCR] [WOS]
  3. (Lin Wan-Chen), Tsai Ming-Chi, Davenport Christopher M., Smith Caleb M., Veit Julia, Wilson Neil M., Adesnik Hillel, Kramer Richard H.* A Comprehensive Optogenetic Pharmacology Toolkit for In Vivo Control of GABA A Receptors and Synaptic Inhibition Neuron 88(5), 879-891 (2015) [JCR] [WOS]
  4. (Lin Wan-Chen), Davenport Christopher M., Mourot Alexandre, Vytla Devaiah, Smith Caleb M., Medeiros Kathryne A., Chambers James J.,* Kramer Richard H.* Engineering a Light-Regulated GABAA Receptor for Optical Control of Neural Inhibition ACS Chemical Biology 9(7), 1414-1419 (2014) [JCR] [WOS]
  5. (Lin Wan-Chen), Licht Stuart* Poly(Ethylene Glycol) as a Scaffold for High-Affinity Open-Channel Blockers of the Mouse Nicotinic Acetylcholine Receptor PLoS ONE 9(11), e112088 (2014) [JCR] [WOS]
  6. Tantama Mathew, (Lin Wan-Chen), Licht Stuart* An Activity-Based Protein Profiling Probe for the Nicotinic Acetylcholine Receptor Journal of the American Chemical Society 130(47), 15766-15767 (2008) [JCR] [WOS]
  7. (Lin Wan-Chen), Licht Stuart* Polymer-Based Open-Channel Blockers for the Acetylcholine Receptor: The Effect of Spacer Length on Blockade Kinetics† Biochemistry 47(35), 9163-9173 (2008) [JCR] [WOS]
  8. Fan Gang-Ting, Pan Yi-shin, Lu Kuo-Cheng, Cheng Yu-Pei, (Lin Wan-Chen), Lin Steven, Lin Chun-Hung, Wong Chi-Huey, Fang Jim-Min, Lin Chun-Cheng Synthesis of α-galactosyl ceramide and the related glycolipids for evaluation of their activities on mouse splenocytes Tetrahedron 61(7), 1855-1862 (2005) [JCR] [WOS]
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李杰龍
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許湉
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王昱舜
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Lopez, Simon Miguel
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