Dr. Lin, Yi-Ling 's orcid link picture Dr. Lin, Yi-Ling 's publons link picture

林宜玲博士

特聘研究員
Division Chief
  • 02-2789-9013 (Lab) (Room No: 443)
  • 02-2652-3902
  • 02-2785-8847 (Fax)
Specialty:
  • Molecular Virology
  • Viral Pathogenesis
  • Viral Immunology
Education and Positions:

  • 1992/12, PhD, University of California, Los Angeles (UCLA), USA

    2014/7-2018/9, Deputy Director, IBMS, AS, Taipei, Taiwan

    2020/9-2024/8, CEO, Emerging Infectious Disease Division (EIDD), Biomedical Translation Research Center (BioTReC), AS, Taipei, Taiwan

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Distinct Antiviral Roles for Human 2',5'-Oligoadenylate Synthetase Family Members against Dengue Virus Infection

Dr. Lin, Yi-Ling
The Journal of Immunology, Nov 18, 2009

The 2`,5`-oligoadenylate synthetase (OAS) and its downstream effector RNase L play important roles in host defense against virus infection. Oas1b, one of the eight Oas1 genes in the mouse genome, has been identified as a murine flavivirus-resistance gene. Four genes, OAS1, OAS2, OAS3, and OAS-like (OASL), have been identified in the human OAS gene family, and 10 isoforms, including OAS1 (p42, p44, p46, p48, and p52), OAS2 (p69 and p71), OAS3 (p100), and OASL (p30 and p59) can be generated by alternative splicing.

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Dr. Lin, Yi-Ling 's Lab