Dr. Yen, Jeffrey J.Y. 's publons link picture

嚴仲陽博士

兼任研究員
  • 02-27899017 (Lab) (Room No: N237)
  • 02-27829142 (Fax)

Specialty:
  • Cytokine Receptor Biology
  • Mouse Disease Model/Phenotyping
  • GVHD/SJS Therapy

Education and Positions:
  • Ph.D. Baylor College of Medicine


Dr. Yen, Jeffrey J.Y. 's
Publications

  1. Chen LY, Lin KR, Chen YJ, Chiang YJ, Ho KC, Shen LF, Song IW, Liu KM, Yang-Yen HF, Chen YJ, Chen YT, Liu FT, (Yen JJY)*. Palmitoyl Acyltransferase Activity of ZDHHC13 Regulates Skin Barrier Development Partly by Controlling PADi3 and TGM1 Protein Stability JOURNAL OF INVESTIGATIVE DERMATOLOGY 140(5),959- (2020-05) [JCR] [WOS]
  2. Yun-Jung Chiang, Wei-Ting Liao, Kun-Chin Ho, Shih-Hao Wang, Yu-Guang Chen, Ching-Liang Ho, Shiu-Feng Huang, Lee-Yung Shih, Hsin-Fang Yang-Yen & Jeffrey Jong-Young Yen CBAP modulates Akt-dependent TSC2 phosphorylation to promote Rheb-mTORC1 signaling and growth of T-cell acute lymphoblastic leukemia. ONCOGENE 38(9), 1432-1447 (2019) [JCR] [WOS]
  3. Liu CS, Yang-Yen HF, Suen CS, Hwang MJ, Yen JJ Cbl-mediated K63-linked ubiquitination of JAK2 enhances JAK2 phosphorylation and signal transduction. Scientific reports 7(1), 4613 (2017) [JCR] [WOS]
  4. Yao L, Mustafa N, Tan EC, Poulsen A, Singh P, Duong-Thi MD, Lee JXT, Ramanujulu PM, Chng WJ, Yen JJY, Ohlson S, Dymock BW Design and Synthesis of Ligand Efficient Dual Inhibitors of Janus Kinase (JAK) and Histone Deacetylase (HDAC) Based on Ruxolitinib and Vorinostat. Journal of medicinal chemistry 60(20), 8336-8357 (2017) [JCR] [WOS]
  5. Chen LY, Yang-Yen HF, Tsai CC, Thio CL, Chuang HL, Yang LT, Shen LF, Song IW, Liu KM, Huang YT, Liu FT, Chang YJ, Chen YT, Yen JJY Protein Palmitoylation by ZDHHC13 Protects Skin against Microbial-Driven Dermatitis. The Journal of investigative dermatology 137(4), 894-904 (2017) [JCR] [WOS]
  6. Shen LF, Chen YJ, Liu KM, Haddad ANS, Song IW, Roan HY, Chen LY, Yen JJY, Chen YJ, Wu JY, Chen YT Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver. Scientific reports 7(1), 2182 (2017) [JCR] [WOS]
  7. Wei Shu-Chen, Yang-Yen Hsin-Fang, Tsao Po-Nien, Weng Meng-Tzu, Tung Chien-Chih, Yu Linda C. H., Lai Liang-Chuan, Hsiao Jen-Hao, Chuang Eric Y., Shun Chia-Tung, Ni Yen-Hsuan, Xavier Ramnik J., Podolsky Daniel K., Yen Jeffery J. Y., Wong Jau-Min SHANK3 Regulates Intestinal Barrier Function Through Modulating ZO-1 Expression Through the PKCε-dependent Pathway Inflammatory Bowel Diseases 23(10), 1730-1740 (2017) [JCR] [WOS]
  8. Yang EG, Mustafa N, Tan EC, Poulsen A, Ramanujulu PM, Chng WJ, Yen JJ, Dymock BW Design and Synthesis of Janus Kinase 2 (JAK2) and Histone Deacetlyase (HDAC) Bispecific Inhibitors Based on Pacritinib and Evidence of Dual Pathway Inhibition in Hematological Cell Lines. Journal of medicinal chemistry 59(18), 8233-62 (2016) [JCR] [WOS]
  9. Lu CH, Wu CJ, Chan CC, Nguyen DT, Lin KR, Lin SJ, Chen LC, Yen JJ, Kuo ML DNA Methyltransferase Inhibitor Promotes Human CD4+CD25hFOXP3+ Regulatory T Lymphocyte Induction under Suboptimal TCR Stimulation. Frontiers in immunology 7, 488 (2016) [JCR] [WOS]
  10. Lin KR, Yang-Yen HF, Lien HW, Liao WH, Huang CJ, Lin LI, Li CL, Yen JJ Murine tribbles homolog 2 deficiency affects erythroid progenitor development and confers macrocytic anemia on mice. Scientific reports 6, 31444 (2016) [JCR] [WOS]