Dr. Chen, Chien-Chang 's orcid link picture Dr. Chen, Chien-Chang 's publons link picture



  • Chronic Pain
  • Calcium Channel
  • Cardiovascular Disease

Education and Positions:
  • Ph.D., University of Illinois, Urbana-Champaign



1. 探討前室丘腦旁核 (PVA) 在慢性疼痛中的作用。我們的研究表明,PVA 參與了幾種囓齒動物模型慢性病的發展和維持。我們正在研究 PVA 如何參與慢性疼痛的神經迴路。

2. 解痛覺過敏啟動的形成。慢性疼痛可由一種或多種急性組織損傷引起,使神經元進入過敏狀態;然而,引發痛覺過敏的機制尚不清楚。我們使用酸誘導的肌肉疼痛 (AIMP) 模型,研究神經元和非神經元細胞在痛覺過敏引發中的角色。

3. 研究衰老是否會加速慢性疼痛的發展或持續時間。

Our Team
Team photo

期刊 56 專書 0

  1. Yeh Hsiao-hui, Chang Yao-Ming, Chang Yu-Wang, Lu Mei-Yeh Jade, Chen Yi-Hua, Lee Chia-Che, Chen Chien-Chang Multiomic analyses reveal enriched glycolytic processes in β-myosin heavy chain-expressed cardiomyocytes in early cardiac hypertrophy Journal of Molecular and Cellular Cardiology Plus 1, 100011 (2022-09) [JCR] [WOS]
  2. Herzig, V.*†, Chen, Y.C.,†, Chin, Y.K.Y., Dekan, Z., Chang, Y-W, Yu, H.M., Alewood, P.F., (Chen, C.C),* and King, G.F.* The Tarantula Toxin ω-Avsp1a Specifically Inhibits Human CaV3.1 and CaV3.3 via the Extracellular S3-S4 Loop of the Domain 1 Voltage-Sensor biomedicines 10(5), 1066 (2022-05-04) [JCR] [WOS]
  3. Tamang, H.K., Yang, R.B., Song, Z.H., Hsu, S.C., Peng, C.C, Tung, Y.C, Tzeng, B.H.*, and (Chen, C.C.)* Cav3.2 T‐type calcium channel regulates mouse platelet activation and arterial thrombosis Journal of Thrombosis and Haemostasis (2022-05-01) [JCR] [WOS]
  4. Chen, W.H., Lien, C.C., (Chen, C.C.)* Neuronal basis for pain- and anxiety-like behaviors in the central nucleus of the amygdala PAIN 163(3), e463-e475 (2022-03-01) [JCR] [WOS]
  5. Hu, Y.F., Lee, A.S., Chang, S.L., Lin, S.F., Weng, C.H., Lo, H.Y., Chou, P.C., Tsai, Y.N., Sung, Y.L., (Chen, C.C.), Yang, R.B., Lin, Y.C. Kuo, T.B., Wu, C.H., Liu, J.D., Chung, T.W., & Chen, S.A. Biomaterial-induced conversion of quiescent cardiomyocytes into pacemaker cells in rats. Nature Biomedical Engineering (2021-11-22) [JCR] [WOS]
  6. Chang, Y.W., Song, Z.H. & (Chen, C.C.)* FAK regulates cardiomyocyte mitochondrial fission and function through Drp1. FEBS JOURNAL (2021-11-05) [JCR] [WOS]
  7. Brandon-Mong, GJ; Shaw, GTW; Chen, WH; (Chen, CC); Wang, DR A network approach to investigating the key microbes and stability of gut microbial communities in a mouse neuropathic pain model BMC MICROBIOLOGY 20(1), 295 (2020-09-30) [JCR] [WOS]
  8. Chang, C.S., Liao, C.C., Liou, A.T., Chang, Y.S., Chang, Y.T., Tzeng, B.H., (Chen, C.C.), & Shih, C. Enterovirus 71 targets the cardiopulmonary system in a robust oral infection mouse model. SCIENTIFIC REPORTS 9(1):11108 (2019-07-31) [JCR] [WOS]
  9. Chang, Y.T., Chen, W.H., Shih, H.C., Shyu, B.C., Min, M.Y. & (Chen, C.C.) Anterior nucleus of paraventricular thalamus mediates chronic mechanical hyperalgesia PAIN 160(5), 1208-1223 (2019-05) [JCR] [WOS]
  10. Huang, I.Y., Hsu, Y.L., (Chen, C.C.), Chen, M.F., Wen, Z.H., Huang, H.T. &Liu, I.Y. Excavatolide-B enhances contextual memory retrieval via repressing the delayed rectifier potassium current in the hippocampus MARINE DRUGS 16(11), 405 (2018-10-25) [JCR] [WOS]

- 博士後研究 -
Chang, Yu-Wang
Chen, Wei-Hsin
- 研究助理 -
Chen, Yong-Cyuan
Song, Zong-Han
- 學生 -
Abdel Aziz, Mohamed Abbas Abdel Hafez
Mindaye, Selomon Assefa
Liang, Shao-Feng
- 昔日夥伴 -
Cheng, Yi-Fen
Chang, Ya-Ting
Yeh, Hsiao-Hui