Dr. Chen, Chih-Cheng 's publons link picture

陳志成博士

副所長
特聘研究員
  • 02-2652-3917
  • 02-2782-9224 (Fax)
Specialty:
  • Pain
  • Neurosensory Mechanotransduction
Education and Positions:

Ph.D. University College London, UK

酸是造成疼痛的主要因子之一，特別是發炎，缺血，腫瘤等引起的慢性疼痛均與組織酸化有關。因此，研究傳遞酸訊息的基因將有助於發展新的止痛對策與藥物。我們過去已經從痛覺神經中陸續選殖出酸的受體基因，並建立了多種酸敏性離子通道的基因剔除小鼠模式。目前主要的研究方向包含:

(1) 探討引起慢性肌肉酸痛的分子機制。

(2) 研究酸敏性離子通道在神經傳導與生理恆定所扮演的角色。

(3) 選殖機械力受體的基因並探討其在慢性酸痛所扮演的角色。

Our Team
Team photo

期刊 102 專書 3

  1. Lee CH, Lin JH, Lin SH, Chang CT, Wu YW, Bewick G, Banks RW, Grunder S, Hochgeschwender U, (Chen CC)* A role for proprioceptors in sngception.. Science advances 11(5), eabc5219 (2025) [JCR] [WOS]
  2. Chuang YC, Jiang BY, (Chen CC)* Effect of Advillin Knockout on Diabetic Neuropathy Induced by Multiple Low Doses of Streptozotocin.. Journal of physiological investigation 68(1), 11-21 (2025) [JCR] [WOS]
  3. Yang CT, Shyu BC, Lin WT, Lu KH, Lin CR, Wen YR, (Chen CC)* Establishing an Electrophysiological Recording Platform for Epidural Spinal Cord Stimulation in Neuropathic Pain Rats.. Journal of pain research 18, 327-340 (2025) [JCR] [WOS]
  4. Sun WZ, (Chen CC)*, Lin JG* When sng meets acupuncture -- a paradigm-shift biomarker for translational research.. Journal of traditional and complementary medicine 15(1), 1-5 (2025) [JCR] [WOS]
  5. Lin YC, Lee CH, Sung JY, (Chen CC)* Genetic exploration of roles of acid-sensing ion channel subtypes in neurosensory mechanotransduction including proprioception.. Experimental physiology 109(1), 66-80 (2024) [JCR] [WOS]
  6. Hung 洪瑋辰 WC, (Chen 陳志成 CC), Yen 嚴震東 CT, Min 閔明源 MY Presynaptic Enhancement of Transmission from Nociceptors Expressing Nav1.8 onto Lamina-I Spinothalamic Tract Neurons by Spared Nerve Injury in Mice.. eNeuro 11(9), ENEURO.0087-24.2024 (2024) [JCR] [WOS]
  7. Lee CH, (Chen CC)* Role of proprioceptors in chronic musculoskeletal pain.. Experimental physiology 109(1), 45-54 (2024) [JCR] [WOS]
  8. Hung CH, Chin Y, Fong YO, Lee CH, Han DS, Lin JH, Sun WH, (Chen CC)* Acidosis-related pain and its receptors as targets for chronic pain.. Pharmacology & therapeutics 247, 108444 (2023) [JCR] [WOS]
  9. Wu CH, Chou WH, Long YH, Yang HH, Lin T, Yang CC, Sun WZ, (Chen CC), Lin CP Development of the Chronic Pain Cognition Scale: A Culture-Sensitive Pain Measurement in Chinese.. Journal of pain research 16, 3075-3084 (2023) [JCR] [WOS]
  10. Han DS, Lee CH, Shieh YD, Chang KV, Lin SH, Chu YC, Wang JL, (Chen CC)* Involvement of ASIC3 and Substance P in Therapeutic Ultrasound-Mediated Analgesia in Mouse Models of Fibromyalgia.. The journal of pain 24(8), 1493-1505 (2023) [JCR] [WOS]
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