Dr. Yang, Shi-Bing 's orcid link picture Dr. Yang, Shi-Bing 's publons link picture

楊世斌博士

長聘副研究員
  • 2652-3532 (Lab) (Room No: N701)

Specialty:
  • Neurophysiology
  • Energy Metabolism
  • Ion channels

Education and Positions:
  • Ph.D, University of Göttingen, Germany (Neuroscience)


離子通道為一群特殊的膜蛋白,不同離子可經由特定的離子通道進出細胞內外。除此之外,透過離子通道的協同運作,會產生不同的生物電現象,例如神經訊號傳導,肌肉收縮以及激素的釋放。最近的大尺度流行病遺傳學分析找出許多致病的離子通道突變,本實驗室藉由結合分子生物學、小鼠遺傳學以及膜片鉗技術,來探討離子通道的基本運作原理,以及離子通道在各式生理以及病理狀態下所扮演的角色。目前主要著重於導致神經系統以及內分泌系統疾病相關離子通道突變的研究。

  1. Athena H. Li, (Shi-Bing Yang)* The caveats and setbacks of mouse genome editing tools in biomedical studies gene reports 33, 101834 (2023-12) [JCR] [WOS]
  2. Athena H Li, (Shi-Bing Yang)* Utilizing Cre-lox-based mouse genetic tools in neuroscience research Gene Reports 33, 101825 (2023-12) [JCR] [WOS]
  3. Cheng-Ting Lee, Wen-Hao Tsai, Chien-Ching Chang, Pei-Chun Chen, Cathy Shen-Jang Fann, Hsueh-Kai Chang, Shih-Yao Liu, Mu-Zon Wu, Pao-Chin Chiu, Wen-Ming Hsu, Wei-Shiung Yang, Ling-Ping Lai, Wen-Yu Tsai, (Shi-Bing Yang)*, Pei-Lung Chen Genotype-phenotype correlation in Taiwanese children with diazoxide-unresponsive congenital hyperinsulinism FRONTIERS IN ENDOCRINOLOGY 14, 1283907 (2023-11) [JCR] [WOS]
  4. Hsu Hong-Ming, Yang Yen-Yu, Huang Yu-Hsin, Chu Chien-Hsin, Tu Ting-Jui, Wu Yen-Ting, Chiang Chu-Jen, (Yang Shi-Bing), Hsu Daniel K., Liu Fu-Tong, Tai Jung-Hsiang Distinct features of the host-parasite interactions between nonadherent and adherent Trichomonas vaginalis isolates PLOS Neglected Tropical Diseases 17(1), e0011016 (2023-01) [JCR] [WOS]
  5. Sandra Postić*, Marko Gosak, Wen-Hao Tsai, Johannes Pfabe, Srdjan Sarikas, Andraž Stožer, Dean Korošak, (Shi-Bing Yang) and Marjan Slak Rupnik pH-Dependence of Glucose-Dependent Activity of Beta Cell Networks in Acute Mouse Pancreatic Tissue Slice FRONTIERS IN ENDOCRINOLOGY 13, 916688 (2022-06-28) [JCR] [WOS]
  6. Wen-Hao Tsai, Cédric Grauffel, Ming-Yueh Huang, Sandra Postić, Marjan Slak Rupnik, Carmay Lim, (Shi-Bing Yang)* Allosteric coupling between transmembrane segment 4 and the selectivity filter of TALK1 potassium channels regulates their gating by extracellular pH JOURNAL OF BIOLOGICAL CHEMISTRY 298(6), 101998 (2022-06-01) [JCR] [WOS]
  7. Yuan-Hung Lin King, Chao Chen, John V. Lin King, Jeffrey Simms, Edward Glasscock, (Shi-Bing Yang), Yuh-Nung Jan, Lily Yeh Jan* Kv1.1 preserves the neural stem cell pool and facilitates neuron maturation during adult hippocampal neurogenesis PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 119(22), 2118240119 (2022-05-25) [JCR] [WOS]
  8. Ching-Han Lin, Yu-Chi Lin, (Shi-Bing Yang)*, Pei-Chun Chen Carbamazepine promotes surface expression of mutant Kir6. 2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy JOURNAL OF BIOLOGICAL CHEMISTRY 298(5), 101904 (2022-05-01) [JCR] [WOS]
  9. Wen-Ching Lin, Hao-Cheng Tang, Han Ying Wang, Chia-Yi Kao, You-Chiun Chang, Athena Hsu Li, (Shi-Bing Yang), and Kurt Yun Mou* Fragment-Directed Random Mutagenesis by the Reverse Kunkel Method ACS SYNTHETIC BIOLOGY 11(4), 1658-1668 (2022-03-24) [JCR] [WOS]
  10. Yu-Ju Chou*, Yu-Kai Ma, Yi-Han Lu, Jung-Tai King, Wen-Sheng Tasi, (Shi-Bing Yang)*, Tsung-Han Kuo* Potential cross-species correlations in social hierarchy and memory between mice and young children Communications Biology 5(230), 1-14 (2022-03-14) [JCR] [WOS]

- 博士後研究 -
Tsai, Wen-Hao
蔡文豪
Li, Athena
李昀潔
- 研究助理 -
Hsu, Yvonne
徐如玉
Su, Amber
蘇亭安
member
吳哲瑋
- 學生 -
Lin, Shih-Che
林士哲
- 昔日夥伴 -
Lu, Kuan-Ming
盧冠名
Chou, Shu-Min
周書民
Lee, Ming-Liang
李明亮
Chen, Hui-Yu
陳薈宇
Tsai, Hsin-Ju
蔡欣汝
Li, Su-Yi
李思儀
member
李以恆