陳垣崇博士

通信研究員
中央研究院院士
  • 02-27899081 (Lab) (Room No: N807)
  • 02-27899085 (Fax)

Specialty:
  • Human Genetics
  • Genomic Medicine

Education and Positions:
  • M.D., Ph.D. Columbia University


Highlight Detail
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Mitochondrial GLUT10 facilitates dehydroascorbic acid import and protects cells against oxidative stress: mechanistic insight into arterial tortuosity syndrome.

Dr. Chen, Yuan-Tsong
Hum. Mol. Genet., Jul 24, 2010

Mutations in glucose transporter 10 (GLUT10) alter angiogenesis and cause arterial tortuosity syndrome (ATS); however, the mechanisms by which these mutations cause disease remain unclear. It has been reported that in most cells, mitochondria are the major source of reactive oxygen species (ROS).