Dr. Shih, Hsiu-Ming 's publons link picture

施修明博士

研究員
  • 2789-9060 (Lab) (Room No: N605)
  • 2652-3520 (Office)
  • 2782-7654 (Fax)

Specialty:
  • Protein-protein Interaction & Modification
  • Cancer Cell Signaling
  • Transcriptional Control

Education and Positions:
  • Ph.D. Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota


Highlight Detail
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Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.

Dr. Shih, Hsiu-Ming
J Cell Biol., Jun 21, 2010

Mitotic spindles play essential roles in chromosome congression and segregation during mitosis. Aurora A regulates spindle assembly in part via phosphorylating human TACC3 on S558, which triggers TACC3 relocalization to mitotic spindles and stabilizes microtubules (MTs).