施修明博士
研究員
- 2789-9060 (Lab) (Room No: N605)
- 2652-3520 (Office)
- 2782-7654 (Fax)
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Specialty:
- Protein-protein Interaction & Modification
- Cancer Cell Signaling
- Transcriptional Control
Education and Positions:
Ph.D. Department of Biochemistry, Molecular Biology, and Biophysics, University of Minnesota
Highlight Detail
Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.
Dr. Shih, Hsiu-Ming
J Cell Biol., Jun 21, 2010Mitotic spindles play essential roles in chromosome congression and segregation during mitosis. Aurora A regulates spindle assembly in part via phosphorylating human TACC3 on S558, which triggers TACC3 relocalization to mitotic spindles and stabilizes microtubules (MTs).