Dr. Chau, Lee-Young 's publons link picture



  • Cardiovascular/Cancer Disease
  • Inflammation

Education and Positions:
  • Ph.D. University of Kentucky

Highlight Detail

Activator Protein-2α Mediates Carbon Monoxide-Induced Stromal Cell-Derived Factor-1α Expression and Vascularization in Ischemic Heart.

Dr. Chau, Lee-Young
Arterioscler Thromb Vasc Biol., Feb 07, 2013

Increased cardiac stromal cell-derived factor-1α (SDF-1α) expression promotes neovascularization and myocardial repair after ischemic injury through recruiting stem cells and reducing cardiomyocyte death. Previous studies have shown that heme oxygenase-1 and its reaction byproduct, carbon monoxide (CO), induce SDF-1α expression in ischemic heart. However, the mechanism underlying heme oxygenase-1/CO-induced cardiac SDF-1α expression remains elusive.