趙麗洋博士
退休研究員
Specialty:
- Cardiovascular/Cancer Disease
- Inflammation
Education and Positions:
Ph.D. University of Kentucky
Highlight Detail
Signal peptide peptidase-mediated nuclear localization of heme oxygenase-1 promotes cancer cell proliferation and invasion independent of its enzymatic activity.
Dr. Chau, Lee-Young
Oncogene., Jun 16, 2014Heme oxygenase-1 (HO-1) is a heme-degrading enzyme anchored in the endoplasmic reticulum by a carboxyl-terminal transmembrane segment (TMS). HO-1 is highly expressed in various cancers and its nuclear localization is associated with the progression of some cancers.