Dr. Chern, Yijuang 's publons link picture Dr. Chern, Yijuang 's Youtube

陳儀莊博士

所長
特聘研究員
  • +886227899028 (Lab) (Room No: N333)
  • +886226523913 (Office)
  • 02-27829143 (Fax)

Specialty:
  • Signal Transduction
  • Gene Regulation
  • Neurodegeneration Disease

Education and Positions:
  • Ph.D. Univ. of Massachusetts


Highlight Detail
...

Energy dysfunction in Huntington's disease: insights from PGC-1α, AMPK, and CKB.

Dr. Chern, Yijuang
Cell Mol Life Sci., May 25, 2012

Huntington's disease (HD) is an autosomal dominant neurodegenerative disease caused by a CAG trinucleotide expansion in the Huntingtin (Htt) gene. When the number of CAG repeats exceeds 36, the translated polyglutamine-expanded Htt protein interferes with the normal functions of many types of cellular machinery and causes cytotoxicity.