Ph.D. Univ. of Massachusetts
The A2A adenosine receptor (A2AR) is a G protein-coupled receptor and a major target of caffeine. The A2AR gene encodes alternative transcripts that are initiated from at least two independent promoters. The different transcripts of the A2AR gene contain the same coding region and 3′-untranslated region and different 5′-untranslated regions that are highly conserved among species.