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EN
謝小燕博士
研究員
02-26523916 (Lab) (Room No: N347)
02-27829143 (Fax)
Specialty:
Cancer Cell Biology
Cell Cycle Signaling
Education and Positions:
Ph.D. Baylor College of Medicine Post-doc:Columbia University
Dr. Shieh, Sheau-Yann 's
Research Highlights
Dr. Shieh, Sheau-Yann 's Lab
Dr. Shieh, Sheau-Yann 's Research Highlights
Requirement for human Mps1/TTK in oxidative DNA damage repair and cell survival through MDM2 phosphorylation.
Nucl. Acids Res., Nov 03, 2015
Phosphorylation at threonine 288 by cell cycle checkpoint kinase 2 (CHK2) controls human monopolar spindle 1 (Mps1) kinetochore localization.
J Biol Chem., Apr 24, 2014
Candidate tumor suppressor BTG3 maintains genomic stability by promoting Lys63-linked ubiquitination and activation of the checkpoint kinase CHK1.
PNAS, Mar 26, 2013
Loss of the candidate tumor suppressor BTG3 triggers acute cellular senescence via the ERK–JMJD3–p16
INK4a
signaling axis.
Oncogene, Oct 24, 2011
p53-Mediated transactivation of LIMK2b links actin dynamics to cell cycle checkpoint control.
Oncogene, Mar 01, 2010
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