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EN
謝小燕博士
研究員
02-26523916 (Lab) (Room No: N347)
02-27829143 (Fax)
Specialty:
Cancer Cell Biology
Cell Cycle Signaling
Education and Positions:
Ph.D. Baylor College of Medicine Post-doc:Columbia University
Dr. Shieh, Sheau-Yann 's
Publications
Dr. Shieh, Sheau-Yann 's Lab
Dr. Shieh, Sheau-Yann 's Publications
期刊
37
專書
2
Begin
~ End
Wen-Cheng Chou, Hui-Chun Wang, Fen-Hwa Wong, Shian-ling Ding, Pei-Ei Wu, Sheau-Yann Shieh*, Chen-Yang Shen*
Chk2-dependent phosphorylation of XRCC1 in the DNA damage response promotes base excision repair.
EMBO J. 27, 3140-3150 (2008-12)
[JCR]
[WOS]
Y. H. Ou, P. H. Chung, F. F. Hsu, T. P. Sun, W. Y. Chang and S. Y. Shieh
The candidate tumor suppressor BTG3 is a transcriptional target of p53 that inhibits E2F1.
EMBO J 26(17), 3968-3980 (2007)
[JCR]
[WOS]
H. C. Wang, W. C. Chou, S. Y. Shieh and C. Y. Shen
Ataxia telangiectasia mutated and checkpoint kinase 2 regulate BRCA1 to promote the fidelity of DNA end-joining.
Cancer Res 66, 1391-1400 (2006)
[JCR]
[WOS]
Y. H. Ou, P. H. Chung, T. P. Sun and S. Y. Shieh
p53 C-Terminal Phosphorylation by CHK1 and CHK2 Participates in the Regulation of DNA-Damage-induced C-Terminal Acetylation.
Mol Biol Cell 16, 1684-1695 (2005)
[JCR]
[WOS]
J. H. Wei, Y. F. Chou, Y. H. Ou, Y. S. Ye, S. W. Tyan, T. P. Sun, C. Y. Shen and S. Y. Shieh
TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.
J Biol Chem 280, 7748-7757 (2005)
[JCR]
[WOS]
V. Gottifredi, S. Shieh, Y. Taya and C. Prives
p53 accumulates but is functionally impaired when DNA synthesis is blocked.
Proceedings of the National Academy of Sciences of the United States of America 98, 1036-1041 (2001)
[JCR]
[WOS]
V. Gottifredi, O. Karni-Schmidt, S. S. Shieh and C. Prives
p53 down-regulates CHK1 through p21 and the retinoblastoma protein.
Mol Cell Biol 21, 1066-1076 (2001)
[JCR]
[WOS]
V. Gottifredi, S. Y. Shieh and C. Prives
Regulation of p53 after different forms of stress and at different cell cycle stages.
Cold Spring Harbor symposia on quantitative biology 65, 483-488 (2000)
[JCR]
[WOS]
S. Y. Shieh, J. Ahn, K. Tamai, Y. Taya and C. Prives
The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.
Genes & Development 14, 289-300 (2000)
[JCR]
[WOS]
R. S. Tibbetts, K. M. Brumbaugh, J. M. Williams, J. N. Sarkaria, W. A. Cliby, S. Y. Shieh, Y. Taya, C. Prives and R. T. Abraham
A role for ATR in the DNA damage-induced phosphorylation of p53.
Genes & Development 13, 152-157 (1999)
[JCR]
[WOS]
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