Dr. Chen, Yen-Hui

Research Scientist
  • 26523058 (Lab) (Room No: 115)
  • 26523018 (Fax)
Specialty:
  • Laboratory Animal Science
  • Mouse phenotyping
  • Cardiovascular disease
Education and Positions:

  • DVM, Dr.med.vet.
    Faculty of Veterinary Medicine, Munich University, Germany

My major duty is to manage the “Laboratory Animal Facility” and the “Pathology Core Laboratory”. My research interest is in pathological phenotyping, through the pathological examinations to realize the histopathological changes and study the pathogenesis. Further, I use echocardiography/ultrasonography to discover phenotype on heart and abdominal organs. Besides, I use microsurgery induced animal model to investigate cardiovascular diseases, e.g. coronary artery ligation induced cardiac infarction, aortic banding induced cardiac hypertrophy, carotid artery injury to mimic restenosis and arthrosclerosis.

Journal 27 Book 0

  1. Ke Hung‐Yen, Chin Li‐Han, Tsai Chien‐Sung, Lin Feng‐Zhi, Chen Yen‐Hui, Chang Yung‐Lung, Huang Shih‐Ming, Chen Yao‐Chang, Lin Chih‐Yuan Cardiac calcium dysregulation in mice with chronic kidney disease Journal of Cellular and Molecular Medicine 24(6),3669-3677 (2020-02) [JCR] [WOS]
  2. Chiang Ming-Tsai, Chen I-Ming, Hsu Fu-Fei, Chen Yen-Hui, Tsai Min-Shao, Hsu Yaw-Wen, Leu Hsin-Bang, Huang Po-Hsun, Chen Jaw-Wen, Liu Fu-Tong, Chen Ying-Hwa, Chau Lee-Young Gal-1 (Galectin-1) Upregulation Contributes to Abdominal Aortic Aneurysm Progression by Enhancing Vascular Inflammation Arteriosclerosis, Thrombosis, and Vascular Biology 41(1), 331-345 (2020) [JCR] [WOS]
  3. Huang Shih-Ting, Wang Yi‑Ping, Chen Yen-Hui, Lin Chin-Tarng, Li Wen-Shan, Wu Han-Chung Liposomal paclitaxel induces fewer hematopoietic and cardiovascular complications than bioequivalent doses of Taxol International Journal of Oncology 53(3), 1105-1117 (2018) [JCR] [WOS]
  4. Cheng Y-F, Chang Y-T, Chen W-H, Shih H-C, (Chen Y-H), Shyu B-C, Chen C-C Cardioprotection induced in mouse model of neuropathic pain via anterior nucleus of paraventricular thalamus. Nature Communications 8(1), 826 (2017) [JCR] [WOS]
  5. Liao W-C, Juo L-Y, Shih Y-L, (Chen Y-H), Yan Y-T HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity. PLOS GENETICS 13(8), e1006984 (2017) [JCR] [WOS]
  6. Hsu YJ, Hsu SC, Hsu CP, (Chen YH), Chang YL, Sadoshima J, Huang SM, Tsai CS, Lin CY Sirtuin 1 protects the aging heart from contractile dysfunction mediated through the inhibition of endoplasmic reticulum stress-mediated apoptosis in cardiac-specific Sirtuin 1 knockout mouse model. International journal of cardiology 228, 543-552 (2017) [JCR] [WOS]
  7. Chin L-H, Hsu Y-J, Hsu S-C, (Chen Y-H), Chang Y-L, Huang S-M, Tsai C-S, Lin C-Y The regulation of NLRP3 inflammasome expression during the development of cardiac contractile dysfunction in chronic kidney disease. Oncotarget 8(69), 113303-113317 (2017) [JCR] [WOS]
  8. Sanjiv K, Chen CW, Kakadiya R, Tala S, Suman S, Wu MH, (Chen YH), Su TL, Lee TC PI3K Inhibition Augments the Therapeutic Efficacy of a 3a-aza-Cyclopenta[alpha]indene Derivative in Lung Cancer Cells. Translational oncology 7(2), 256-266.e5 (2014) [JCR] [WOS]
  9. Lin HH, (Chen YH), Chiang MT, Huang PL, Chau LY Activator protein-2alpha mediates carbon monoxide-induced stromal cell-derived factor-1alpha expression and vascularization in ischemic heart. Arteriosclerosis Thrombosis and Vascular Biology 33(4), 785-794 (2013) [JCR] [WOS]
  10. Chang YC, Yu YH, Shew JY, Lee WJ, Hwang JJ, (Chen YH), Chen YR, Wei PC, Chuang LM, Lee WH Deficiency of NPGPx, an oxidative stress sensor, leads to obesity in mice and human. EMBO molecular medicine 5(8), 1165-1179 (2013) [JCR] [WOS]
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