Neuroscience
Cardiovascular & Metabolic Diseases
Infectious Disease & Immunology
Cancer
Research Highlights
Dr. Chang, Ya-Jen
Cell Reports, Sep 27, 2022
The ketone body β-hydroxybutyrate mitigates ILC2-driven airway inflammation by regulating mast ......
Ketone bodies are increasingly understood to have regulatory effects on immune cell function, with β-hydroxybutyrate (BHB) exerting a predominantly anti-inflammatory response. Dietary strategies to increase endogenous ketone body avail ...... MORE
Dr. Hsieh, Patrick Ching-Ho
Biomaterials, Sep 19, 2022
The gut microbiota regulates acute foreign body reaction and tissue repair after biomaterial i ......
We hypothesized that the host microbiome may influence foreign body responses following biomaterial implantation. To test this, we implanted a variety of clinically relevant biomaterials into germ-free or antibiotic-trea ...... MORE
Dr. Yang, Kai-Chien
Journal of Biomedical Science, Sep 02, 2022
The novel role of ER protein TXNDC5 in the pathogenesis of organ fibrosis: mechanistic insight ......
Fibrosis-related disorders account for an enormous burden of disease-associated morbidity and mortality worldwide. Fibrosis is defined by excessive extracellular matrix deposition at fibrotic foci in the organ ...... MORE
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