Neuroscience
Cardiovascular & Metabolic Diseases
Infectious Disease & Immunology
Cancer
Research Highlights
Dr. Shih, Chiaho
Journal of Biomedical Science, Jun 21, 2022
Hepatitis B virus virion secretion is a CRM1-spike-mediated late event
Background: Hepatitis B virus (HBV) is a major human pathogen worldwide. To date, there is no curative treatment for chronic hepatitis B. The mechanism of virion secretion remains to be investigated. Previ ...... MORE
Dr. Shih, Hsiu-Ming
Cellular and Molecular Life Sciences, Jun 19, 2022
Reciprocal regulation of Daxx and PIK3CA promotes colorectal cancer cell growth
Upregulation of death-domain-associated protein (Daxx) is strongly associated with diverse cancer types. Among these, the clinicopathological significance and molecular mechanisms of Daxx overexpression in colo ...... MORE
Dr. Hsieh, Patrick Ching-Ho
Cells, Jun 06, 2022
Utility of iPSC-Derived Cells for Disease Modeling, Drug Development, and Cell Therapy
The advent of induced pluripotent stem cells (iPSCs) has advanced our understanding of the molecular mechanisms of human disease, drug discovery, and regenerative medicine. As such, the use of iPSCs in drug dev ...... MORE
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