2024 Highlights

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Dr. Huang , Yi-Shuian
CPEB2-activated Prdm16 translation promotes brown adipocyte function and prevents obesity
Molecular Metabolism Sep 20, 2024

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Dr. Chern , Yijuang
Metabolic dysregulation in Huntington's disease: Neuronal and glial perspectives
Neurobiology of Disease Sep 19, 2024

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Dr. Lim , Carmay
PPI-hotspotID for detecting protein-protein interaction hot spots from the free protein structure
eLife Sep 16, 2024

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Dr. Suzuki , Jun
Phospholipid scrambling induced by an ion channel/metabolite transporter complex
Nature Communications Aug 31, 2024

Cells establish the asymmetrical distribution of phospholipids and alter their distribution by phospholipid scrambling (PLS) to adapt to env ...

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Dr. Chen , Chien-Chang
Exploring the role of spinal astrocytes in the onset of hyperalgesic priming signals in acid-induced chronic muscle pain
PNAS Nexus Aug 30, 2024

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Dr. Roffler , Steve R.
Liposomes with Low Levels of Grafted Poly(ethylene glycol) Remain Susceptible to Destabilization by Anti-Poly(ethylene glycol) Antibodies
ACS Nano Aug 09, 2024

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Dr. Lee , Kuo-Sheng
Transformation of neural coding for vibrotactile stimuli along the ascending somatosensory pathway
Neuron Aug 06, 2024

In mammals, action potentials fired by rapidly adapting mechanosensitive afferents are known to reliably time lock to the cycles of a vibrat ...

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Dr. Huang , Yi-Shuian
CPEB2-activated axonal translation of VGLUT2 mRNA promotes glutamatergic transmission and presynaptic plasticity
Journal of Biomedical Science Jul 11, 2024

Background: Local translation at synapses is important for rapidly remodeling the synaptic proteome to sustain long-term plasticity and ...

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Dr. Hu , Che-Ming (Jack)
High-Affinity Superantigen-Based Trifunctional Immune Cell Engager Synergizes NK and T Cell Activation for Tumor Suppression
Advanced Science Jun 27, 2024

The development of immune cell engagers (ICEs) can be limited by logistical and functional restrictions associated with fusion protein desig ...

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Dr. Lee , Eminy H.Y.
Novel role of NCoR1 in impairing spatial memory through the mediation of a novel interacting protein DEC2
Cellular and Molecular Life Sciences Jun 20, 2024

Long-term memory formation requires de novo RNA and protein synthesis. Using differential display PCR, we found that the NCoR1 cDN ...

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