Dr. Yang, Pan-Chyr

MicroRNA Signature Predicts Survival and Relapse in Lung Cancer.

Cancer Cell, Jan 08, 2008

We investigated whether microRNA expression profiles can predict clinical outcome of NSCLC patients.Using real-time RT-PCR, we obtained


Dr. Shih, Hsiu-Ming

SUMO modification negatively modulates the transcriptional activity of CREB-binding protein via the recruitment of Daxx.

PNAS., Nov 22, 2005

Small ubiquitin-like modifier (SUMO) modification is emerging as an important control in transcription regulation.Here, we show that CREB ......


Dr. Tarn, Woan-Yuh

Exon Selection in a-Tropomyosin mRNA Is Regulated by the Antagonistic Action of RBM4 and PTB.

Molecular and Cellular Biology, Nov 01, 2005

RNA-binding motif protein 4 (RBM4) has been implicated in the regulation of precursor mRNA splicing. Using differential display analysis, ......


Dr. Cheng, Andrew Tai Ann

A 3-Year Panel Study of Mental Disorders Among Adolescents in Taiwan

Am J Psychiatry., Jul 01, 2005

This study investigated the prevalence and changing trends of mental disorders and the effects of gender and urbanization among adolescents ......


Dr. Chen, Yuan-Tsong

A novel functional VKORC1 promoter polymorphism is associated with inter-individual and inter-ethnic differences in warfarin sensitivity.

Human Molecular Genetics., May 11, 2005

Warfarin, a commonly prescribed anticoagulant, exhibited large inter-individual and inter-ethnic differences in the dose required for its ......


Dr. Chen, Yuan-Tsong

HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol.

PNAS., Mar 15, 2005

Allopurinol, a commonly prescribed medication for gout and hyperuricemia, is a frequent cause of severe cutaneous adverse reactions (SCAR ......


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