HLA-B*5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol.
Dr. Chen, Yuan-Tsong
PNAS., Mar 15, 2005
Allopurinol, a commonly prescribed medication for gout and hyperuricemia, is a frequent cause of severe cutaneous adverse reactions (SCAR), which include the drug hypersensitivity syndrome, Stevens–Johnson syndrome