Dr. Shieh, Sheau-Yann

JAK2-CHK2 signaling safeguards the integrity of the mitotic spindle assembly checkpoint and genome stability

Cell Death & Disease, Jul 18, 2022

      Checkpoint kinase 2 (CHK2) plays an important role in safeguarding the mitotic progression, specifically the s ......


Dr. Lin, Jung-Hsin

A Curvilinear-Path Umbrella Sampling Approach to Characterizing the Interactions Between Rapamycin and Three FKBP12 Variants

Frontiers in Molecular Biosciences, Jul 08, 2022

      Rapamycin is an immunosuppressant macrolide that exhibits anti-proliferative properties through inhibiting the ......


Dr. Tao, Mi-Hua

A booster dose of Delta × Omicron hybrid mRNA vaccine produced broadly neutralizing antibody against Omicron and other SARS-CoV-2 variants

Journal of Biomedical Science, Jul 07, 2022

      Background: With the continuous emergence of new SARS-CoV-2 variants that feature increased transmissio ......


Dr. Pan, Wen-Harn

Healthy Taiwanese Eating Approach (TEA) toward Total Wellbeing and Healthy Longevity

Nutrients, Jul 05, 2022

      A healthy dietary pattern review for Asian countries is scarce, which is crucial for guiding healthy eating. W ......


Dr. Chen, Huan-Yuan

Galectin-3 facilitates cell-to-cell HIV-1 transmission by altering the composition of membrane lipid rafts in CD4 T cells

Glycobiology, Jul 05, 2022

      Galectin-3 (GAL3) is a β-galactoside-binding lectin expressed in CD4 T cells infected with human immunode ......


Dr. Chen, Chien-Chang

Cav3.2 T-type calcium channel regulates mouse platelet activation and arterial thrombosis

Journal of thrombosis and haemostasis, Jul 01, 2022

      Background Cav3.2 is a T-type calcium channel that causes low-threshold exocytosis. T-type calcium channe ......


Dr. Chen, Chien-Chang

Multiomic analyses reveal enriched glycolytic processes in β-myosin heavy chain-expressed cardiomyocytes in early cardiac hypertrophy

Journal of Molecular and Cellular Cardiology Plus, Jun 27, 2022

      Background Cardiac pressure overload induces cardiac hypertrophy and eventually leads to heart ......


Dr. Hu, Yu-Feng

Fibroblasts Drive Metabolic Reprogramming in Pacemaker Cardiomyocytes

Circulation Research, Jun 24, 2022

      Methods: Tbx18 (T-box transcription factor 18)-induced PCs and fibroblasts were used for cocultures and e ......


Dr. Shih, Chiaho

Hepatitis B virus virion secretion is a CRM1-spike-mediated late event

Journal of Biomedical Science, Jun 21, 2022

      Background: Hepatitis B virus (HBV) is a major human pathogen worldwide. To date, there is no curative tr ......


Dr. Shih, Hsiu-Ming

Reciprocal regulation of Daxx and PIK3CA promotes colorectal cancer cell growth

Cellular and Molecular Life Sciences, Jun 19, 2022

      Upregulation of death-domain-associated protein (Daxx) is strongly associated with diverse cancer types. Among ......


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