Dr. Yang, Ruey-Bing (Ray)

Receptor guanylyl cyclase‐G is a novel thermosensory protein activated by cool temperatures.

EMBO J., Dec 01, 2014

Transmembrane guanylyl cyclases (GCs), with activity regulated by peptide ligands and/or calcium‐binding proteins, are essential for various ......


Dr. Tarn, Woan-Yuh

Alanine repeats influence protein localization in splicing speckles and paraspeckles.

Nucleic Acids Res., Nov 20, 2014

Mammalian splicing regulatory protein RNA-binding motif protein 4 (RBM4) has an alanine repeat-containing C-terminal domain (CAD) that confe ......


Dr. Hsieh, Patrick Ching-Ho

Circulating Cells Contribute to Cardiomyocyte Regeneration After Injury.

Circ Res., Nov 14, 2014

Rationale: The contribution of bone marrow-borne hematopoietic cells to the ischemic myocardium has been documented. However, a pivotal stud ......


Dr. Lim, Carmay

Ion Selectivity Strategies of Sodium Channel Selectivity Filters.

Acc Chem Res., Oct 24, 2014

Conspectus Sodium ion channels selectively transport Na+ cations across the cell membrane. These integral parts of the cell machinery are im ......


Dr. Tarn, Woan-Yuh

TRAP150 activates splicing in composite terminal exons.

Nucl. Acids Res., Oct 17, 2014

The spliceosomal factor TRAP150 is essential for pre-mRNA splicing in vivo and, when overexpressed, it enhances splicing efficiency. In this ......


Dr. Chern, Yijuang

Activation of AMP- activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis.

Hum Mol Genet., Sep 25, 2014

TAR DNA-binding protein-43 (TDP-43) is a nuclear RNA-binding protein involved in many cellular pathways. TDP-43-positive inclusions are a ha ......


Dr. Tai, Jung-Hsiang

Signal transduction triggered by iron to induce the nuclear importation of a Myb3 transcription factor in the parasitic protozoan, Trichomonas vaginalis.

J Biol Chem., Sep 02, 2014

Iron was previously shown to induce rapid nuclear translocation of a Myb3 transcription factor in the protozoan parasite, Trichomonas vagina ......


Dr. Shih, Chiaho

Immunodeficient Mouse Models with Different Disease Profiles by in vivo Infection with the Same Clinical Isolate of Enterovirus 71.

J Virol., Aug 20, 2014

Like poliovirus, severe infection with enterovirus 71 (EV71) can cause neuropathology. Unlike poliovirus, EV71 is often associated with hand ......


Dr. Tarn, Woan-Yuh

DDX3 modulates cell adhesion and motility and cancer cell metastasis via Rac1-mediated signaling pathway.

Oncogene., Jul 21, 2014

The DEAD-box RNA helicase DDX3 is a versatile protein involved in multiple steps of gene expression and various cellular signaling pathways. ......


Dr. Lee, Eminy H.Y.

CREB SUMOylation by the E3 Ligase PIAS1 Enhances Spatial Memory.

J. Neurosci., Jul 16, 2014

cAMP-responsive element binding protein (CREB) phosphorylation and signaling plays an important role in long-term memory formation, but othe ......


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