Dr. Yang, Ruey-Bing (Ray)Receptor guanylyl cyclase‐G is a novel thermosensory protein activated by cool temperatures.
EMBO J., Dec 01, 2014Transmembrane guanylyl cyclases (GCs), with activity regulated by peptide ligands and/or calcium‐binding proteins, are essential for various ......
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Dr. Tarn, Woan-Yuh Alanine repeats influence protein localization in splicing speckles and paraspeckles.
Nucleic Acids Res., Nov 20, 2014Mammalian splicing regulatory protein RNA-binding motif protein 4 (RBM4) has an alanine repeat-containing C-terminal domain (CAD) that confe ......
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Dr. Hsieh, Patrick Ching-Ho Circulating Cells Contribute to Cardiomyocyte Regeneration After Injury.
Circ Res., Nov 14, 2014Rationale: The contribution of bone marrow-borne hematopoietic cells to the ischemic myocardium has been documented. However, a pivotal stud ......
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Dr. Lim, Carmay Ion Selectivity Strategies of Sodium Channel Selectivity Filters.
Acc Chem Res., Oct 24, 2014Conspectus Sodium ion channels selectively transport Na+ cations across the cell membrane. These integral parts of the cell machinery are im ......
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Dr. Tarn, Woan-Yuh TRAP150 activates splicing in composite terminal exons.
Nucl. Acids Res., Oct 17, 2014The spliceosomal factor TRAP150 is essential for pre-mRNA splicing in vivo and, when overexpressed, it enhances splicing efficiency. In this ......
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Dr. Chern, Yijuang Activation of AMP- activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis.
Hum Mol Genet., Sep 25, 2014TAR DNA-binding protein-43 (TDP-43) is a nuclear RNA-binding protein involved in many cellular pathways. TDP-43-positive inclusions are a ha ......
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Dr. Tai, Jung-Hsiang Signal transduction triggered by iron to induce the nuclear importation of a Myb3 transcription factor in the parasitic protozoan, Trichomonas vaginalis.
J Biol Chem., Sep 02, 2014Iron was previously shown to induce rapid nuclear translocation of a Myb3 transcription factor in the protozoan parasite, Trichomonas vagina ......
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Dr. Shih, Chiaho Immunodeficient Mouse Models with Different Disease Profiles by in vivo Infection with the Same Clinical Isolate of Enterovirus 71.
J Virol., Aug 20, 2014Like poliovirus, severe infection with enterovirus 71 (EV71) can cause neuropathology. Unlike poliovirus, EV71 is often associated with hand ......
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Dr. Tarn, Woan-Yuh DDX3 modulates cell adhesion and motility and cancer cell metastasis via Rac1-mediated signaling pathway.
Oncogene., Jul 21, 2014The DEAD-box RNA helicase DDX3 is a versatile protein involved in multiple steps of gene expression and various cellular signaling pathways. ......
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Dr. Lee, Eminy H.Y. CREB SUMOylation by the E3 Ligase PIAS1 Enhances Spatial Memory.
J. Neurosci., Jul 16, 2014cAMP-responsive element binding protein (CREB) phosphorylation and signaling plays an important role in long-term memory formation, but othe ......
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