楊瑞彬 博士Receptor guanylyl cyclase‐G is a novel thermosensory protein activated by cool temperatures.
EMBO J., Dec 01, 2014
Transmembrane guanylyl cyclases (GCs), with activity regulated by peptide ligands and/or calcium‐binding proteins, are essential for various ......
譚婉玉 博士Alanine repeats influence protein localization in splicing speckles and paraspeckles.
Nucleic Acids Res., Nov 20, 2014
Mammalian splicing regulatory protein RNA-binding motif protein 4 (RBM4) has an alanine repeat-containing C-terminal domain (CAD) that confe ......
謝清河 博士Circulating Cells Contribute to Cardiomyocyte Regeneration After Injury.
Circ Res., Nov 14, 2014
Rationale: The contribution of bone marrow-borne hematopoietic cells to the ischemic myocardium has been documented. However, a pivotal stud ......
林小喬 博士Ion Selectivity Strategies of Sodium Channel Selectivity Filters.
Acc Chem Res., Oct 24, 2014
Conspectus Sodium ion channels selectively transport Na+ cations across the cell membrane. These integral parts of the cell machinery are im ......
譚婉玉 博士TRAP150 activates splicing in composite terminal exons.
Nucl. Acids Res., Oct 17, 2014
The spliceosomal factor TRAP150 is essential for pre-mRNA splicing in vivo and, when overexpressed, it enhances splicing efficiency. In this ......
陳儀莊 博士Activation of AMP- activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis.
Hum Mol Genet., Sep 25, 2014
TAR DNA-binding protein-43 (TDP-43) is a nuclear RNA-binding protein involved in many cellular pathways. TDP-43-positive inclusions are a ha ......
戴榮湘 博士Signal transduction triggered by iron to induce the nuclear importation of a Myb3 transcription factor in the parasitic protozoan, Trichomonas vaginalis.
J Biol Chem., Sep 02, 2014
Iron was previously shown to induce rapid nuclear translocation of a Myb3 transcription factor in the protozoan parasite, Trichomonas vagina ......
施嘉和 博士Immunodeficient Mouse Models with Different Disease Profiles by in vivo Infection with the Same Clinical Isolate of Enterovirus 71.
J Virol., Aug 20, 2014
Like poliovirus, severe infection with enterovirus 71 (EV71) can cause neuropathology. Unlike poliovirus, EV71 is often associated with hand ......
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