陳儀莊 博士

Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy

Acta Neuropathologica Communications, Jun 25, 2021

Tau pathology is instrumental in the gradual loss of neuronal functions and cognitive decline in tauopathies, including Alzheimer’s di ......

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蔡松智 博士

Epitranscriptomic addition of m6A regulates HIV-1 RNA stability and alternative splicing

Genes & Development, Jun 17, 2021

    Previous work has demonstrated that the epitranscriptomic addition of m6A to viral transcripts can promote the replicati ......

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唐堂 博士

Human Microcephaly Protein RTTN Is Required for Proper Mitotic Progression and Correct Spindle Position

Cells, Jun 09, 2021

    Autosomal recessive primary microcephaly (MCPH) is a complex neurodevelopmental disorder characterized by a small brain ......

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胡哲銘 博士

Facile Transformation of Murine and Human Primary Dendritic Cells into Robust and Modular Artificial Antigen-Presenting Systems by Intracellular Hydrogelation

Advanced Materials, Jun 07, 2021

    The growing enthusiasm for cancer immunotherapies and adoptive cell therapies has prompted increasing interest in biom ......

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沈志陽 博士

MiR-139 Modulates Cancer Stem Cell Function of Human Breast Cancer through Targeting CXCR4

Cancers , May 25, 2021

  Simple Summary The C-X-C motif chemokine receptor 4 (CXCR4) is overexpressed in various cancer stem/progenitor cells via ......

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楊世斌 博士

Kv1.1 channels regulate early postnatal neurogenesis in mouse hippocampus via the TrkB signaling pathway

eLife, May 21, 2021

    In the postnatal brain, neurogenesis occurs only within a few regions, such as the hippocampal sub-granular zone (SGZ). ......

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鄭泰安 博士

Genome-wide association study of early-onset bipolar I disorder in the Han Taiwanese population

Translational Psychiatry, May 20, 2021

    The search for susceptibility genes underlying the heterogeneous bipolar disorder has been inconclusive, often with irre ......

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李家偉 博士

Epithelial-mesenchymal transition induced by SARS-CoV-2 required transcriptional upregulation of Snail

American Journal of Cancer Research, May 15, 2021

    The engagement of human angiotensin-converting enzyme 2 (hACE2) and SARS-CoV-2 spike protein facilitate virus spread. Th ......

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黃怡萱 博士

CPEB3-downregulated Nr3c1 mRNA translation confers resilience to developing posttraumatic stress disorder-like behavior in fear-conditioned mice

Neuropsychopharmacology, May 03, 2021

    Susceptibility or resilience to posttraumatic stress disorder (PTSD) depends on one's ability to appropriately adjus ......

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謝清河 博士

Immune cell shuttle for precise delivery of nanotherapeutics for heart disease and cancer

Science Advances, Apr 23, 2021

      The delivery of therapeutics through the circulatory system is one of the least arduous and less invasive inte ......

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