黃明經 博士A Critical Assessment of Information-guided Protein-protein Docking Predictions.
Mol Cell Proteomics., Dec 13, 2012
The structures of protein complexes are increasingly predicted by protein-protein docking (PPD) using ambiguous interaction data to help gui ......
施修明 博士The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability.
Oncogene, Dec 03, 2012
Acute promyelocytic leukemia (APL) is predominantly characterized by chromosomal translocations between the retinoic acid receptor, alpha (R ......
劉扶東 博士Galectin-3 Regulates Intracellular Trafficking of EGFR through Alix and Promotes Keratinocyte Migration.
Journal of Investigative Dermatology, Dec 01, 2012
The EGFR-mediated signaling pathways are important in a variety of cellular processes, including cell migration and wound re-epithelializati ......
鄭泰安 博士Changing trends in the prevalence of common mental disorders in Taiwan: a 20-year repeated cross-sectional survey.
The Lancet, Nov 12, 2012
The term common mental disorders (CMDs) is a broad diagnostic category for non-psychotic, depressive, and anxiety disorders that covers most ......
謝清河 博士Xenografted human amniotic fluid-derived stem cell as a cell source in therapeutic angiogenesis.
Int J Cardiol., Oct 06, 2012
The AFSC-ECs demonstrated endothelial cell characteristics in vitro. Four weeks later, AFSC-ECs transplantation significantly increased limb ......
陳垣崇 博士Pharmacogenomics of adverse drug reactions: implementing personalized medicine.
Hum Mol Genet., Aug 19, 2012
Pharmacogenomics aims to investigate the genetic basis of inter-individual differences in drug responses, such as efficacy, dose requirement ......
陳建璋 博士The Cav3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.
Cardiovasc Res., Aug 10, 2012
Restenosis is an undesirable consequence following percutaneous vascular interventions. However, the current strategy for preventing resteno ......
謝清河 博士Instructive Nanofiber Scaffolds with VEGF Create a Microenvironment for Arteriogenesis and Cardiac Repair.
Sci Transl Med., Aug 08, 2012
Angiogenic therapy is a promising approach for tissue repair and regeneration. However, recent clinical trials with protein delivery or gene ......
謝清河 博士Treatment of acute thromboembolism in mice using heparin-conjugated carbon nanocapsules.
ACS Nano., Jul 24, 2012
The unsurpassed properties in electrical conductivity, thermal conductivity, strength, and surface area-to-volume ratio allow for many poten ......
周玉山 博士HDAC inhibitors augmented cell migration and metastasis through induction of PKCs leading to identification of low toxicity modalities for combination cancer therapy.
Clin Cancer Res., Jul 18, 2012
Histone deacetylase inhibitors (HDACi) are actively explored as new-generation epigenetic drugs but have low efficacy in cancer monotherapy. ......
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