2022 成果

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沈志陽 博士
Inhibitory Effects of Ursolic Acid on the Stemness and Progression of Human Breast Cancer Cells by Modulating Argonaute-2
International Journal of Molecular Sciences Dec 26, 2022

      The stemness and metastasis of cancer cells are crucial features in determining cancer progression. Argonaute- ...

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陶秘華 博士
A receptor-binding domain-based nanoparticle vaccine elicits durable neutralizing antibody responses against SARS-CoV-2 and variants of concern
Emerging Microbes & Infections Dec 24, 2022

      Numerous vaccines have been developed to address the current COVID-19 pandemic, but safety, cross-neutralizing ...

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張雅貞 博士
Identification of a PD-L1+Tim-1+ iNKT subset that protects against fine particulate matter–induced airway inflammation
JCI Insight Dec 08, 2022

      Although air pollutants such as fine particulate matter (PM2.5) are associated with acute and chronic lung inf ...

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潘文涵 博士
Dietary Characteristics of Elders with Frailty and with Mild Cognitive Impairment: Cross-Sectional Findings and Implications from the Nutrition and Health Survey in Taiwan 2014-2017
Nutrients Dec 07, 2022

      It is unclear whether low dietary intake accompanied with multiple nutrient deficiencies or specific nutrient ...

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李永凌 博士
Association of the consumption of common drinks with early puberty in both sexes
Frontiers in Public Health Dec 02, 2022

      Background: We examined the effect of sugar-sweetened beverages (SSB) and common drink intake on pubertal ...

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周玉山 博士
Somatic A-to-I RNA-edited RHOA isoform 2 specific-R176G mutation promotes tumor progression in lung adenocarcinoma
Molecular Carcinogenesis Dec 01, 2022

      Adenosine-to-inosine (A-to-I) RNA editing is the most common posttranscriptional editing to create somatic mut ...

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胡哲銘 博士
In Situ Hydrogelation of Cellular Monolayers Enables Conformal Biomembrane Functionalization for Xeno-Free Feeder Substrate Engineering
Advanced Healthcare Materials Dec 01, 2022

      The intricate biochemical functionalities of cellular membranes have inspired numerous strategies for deriving ...

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謝清河 博士
Metabolic Changes Associated With Cardiomyocyte Dedifferentiation Enable Adult Mammalian Cardiac Regeneration
Circulation Nov 24, 2022

        BACKGROUND: Cardiac regeneration after injury is limited by the low proliferative capacity of adu ...

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范盛娟 博士
Genome-wide analyses identify novel risk loci for cluster headache in Han Chinese residing in Taiwan
Journal of Headache and Pain Nov 21, 2022

      Background: Cluster headache is a highly debilitating neurological disorder with considerable inter-ethni ...

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潘文涵 博士
Pharmacometabolomic study of drug response to antihypertensive medications for hypertension marker identification in Han Chinese individuals in Taiwan
Computational and Structural Biotechnology Journal Nov 17, 2022

      Various groups of antihypertensive drugs targeting different pathways have been developed; however, the pharma ...

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